Growth inhibitory effect of dihydroartemisinin on Bcr/Abl+ chronic myeloid leukemia K562 cells involve AKT, ERK and NF-κB modulation (Q39308078)

10 September 2017

title

Growth inhibitory effect of dihydroartemisinin on Bcr/Abl+ chronic myeloid leukemia K562 cells involve AKT, ERK and NF-κB modulation (English)

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10 September 2017

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chronic myeloid leukemia

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Jun Lee

1

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10 September 2017

Guobing Zhang

2

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10 September 2017

Xiuhua Wu

3

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10 September 2017

Feilong Xu

4

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10 September 2017

Jun Zhou

5

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10 September 2017

Xingguo Zhang

6

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10 September 2017

publication date

26 July 2012

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Journal of Cancer Research and Clinical Oncology

10 September 2017

published in

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10 September 2017

volume

138

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10 September 2017

issue

12

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10 September 2017

page(s)

2095-2102

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https://scigraph.springernature.com/pub.10.1007/s00432-012-1292-1

10 September 2017

exact match

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cites work

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Dihydroartemisinin downregulates vascular endothelial growth factor expression and induces apoptosis in chronic myeloid leukemia K562 cells

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Single-cell analysis of dihydroartemisinin–induced apoptosis through reactive oxygen species–mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques

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Targeting leukemic fusion proteins with small interfering RNAs: recent advances and therapeutic potentials

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Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo.

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Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathway.

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Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells

21 January 2018

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12 December 2020

Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo

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12 December 2020

Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3

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12 December 2020

Pharmacokinetics of artemisinin and artesunate after oral administration in healthy volunteers.

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BCR-ABL delays apoptosis upstream of procaspase-3 activation

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12 December 2020

The development of new antimalarial drugs: qinghaosu and dihydro-qinghaosu

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12 December 2020

Signaling networks associated with BCR-ABL-dependent transformation

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12 December 2020

Mechanisms of primary and secondary resistance to imatinib in chronic myeloid leukemia

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12 December 2020

10.1007/S00432-012-1292-1

Identifiers

DOI

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10 September 2017

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