Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide (Q39308847)

10 September 2017

title

Methoxyamine sensitizes the resistant glioblastoma T98G cell line to the alkylating agent temozolomide (English)

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10 September 2017

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Elza T Sakamoto-Hojo

2

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author name string

Ana P Montaldi

series ordinal

1

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10 September 2017

publication date

25 July 2012

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Clinical and Experimental Medicine

10 September 2017

published in

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10 September 2017

volume

13

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10 September 2017

issue

4

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10 September 2017

page(s)

279-288

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Genetic pathways to primary and secondary glioblastoma

10 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Malignant astrocytic glioma: genetics, biology, and paths to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Triazene compounds: mechanism of action and related DNA repair systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Contribution of O6‐methylguanine‐DNA methyltransferase to monofunctional alkylating‐agent resistance in human brain tumor—derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Pharmacological strategies to increase the antitumor activity of methylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Mammalian DNA beta-polymerase in base excision repair of alkylation damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

DNA repair inhibition: a selective tumour targeting strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Processing in vitro of an abasic site reacted with methoxyamine: a new assay for the detection of abasic sites formed in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Targeting base excision repair for chemosensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

DNA repair and cancer stem-like cells--potential partners in glioma drug resistance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Targeted cancer therapies based on the inhibition of DNA strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Clonogenic assay of cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

A simple technique for quantitation of low levels of DNA damage in individual cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Contribution of DNA repair mechanisms to determining chemotherapy response in high-grade glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Going ape as an approach to cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Phase I and pharmacokinetic study of temozolomide on a daily-for-5-days schedule in patients with advanced solid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Temozolomide: a novel oral alkylating agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Induction of autophagy in temozolomide treated malignant gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Acquired resistance to temozolomide in glioma cell lines: molecular mechanisms and potential translational applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Fen1 expression: a novel marker for cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Cleavage of substrates with mismatched nucleotides by Flap endonuclease-1. Implications for mammalian Okazaki fragment processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Proliferating cell nuclear antigen (PCNA): a dancer with many partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

Promoter methylation and polymorphisms of the MGMT gene in glioblastomas: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10238-012-0201-X

The mechanism of switching among multiple BER pathways.

21 January 2018

1 reference

12 December 2020

A new approach to the study of the base-excision repair pathway using methoxyamine

1 reference

12 December 2020

Base Excision Repair and its Role in Maintaining Genome Stability

1 reference

12 December 2020

Clinical significance of molecular biomarkers in glioblastoma

1 reference

12 December 2020

Repair of O(6)-alkylguanine by alkyltransferases

1 reference

12 December 2020

Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.

1 reference

12 December 2020

Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts

1 reference

12 December 2020

Mutagenic processing of ethylation damage in mammalian cells: the use of methoxyamine to study apurinic/apyrimidinic site-induced mutagenesis

1 reference

12 December 2020

Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents

1 reference

12 December 2020

Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells

1 reference

12 December 2020

New treatment strategies for malignant gliomas

1 reference

12 December 2020

Biology and treatment of malignant glioma

1 reference

12 December 2020

Chemotherapy of brain tumors

1 reference

12 December 2020

Multifaceted resistance of gliomas to temozolomide.

1 reference

12 December 2020

Reaction of apurinic/apyrimidinic sites with [14C]methoxyamine. A method for the quantitative assay of AP sites in DNA

1 reference

12 December 2020

Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas.

1 reference

12 December 2020

p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells

1 reference

12 December 2020

Apurinic/apyrimidinic endonuclease expression in pediatric yolk sac tumors

1 reference

12 December 2020

Base excision repair as a therapeutic target in colon cancer.

1 reference

12 December 2020

Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma

1 reference

12 December 2020

Mammalian base excision repair and DNA polymerase beta

1 reference

12 December 2020

O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy

1 reference

12 December 2020

Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer

1 reference

12 December 2020

Role of O6-methylguanine-DNA methyltransferase in resistance of human brain tumor cell lines to the clinically relevant methylating agents temozolomide and streptozotocin

1 reference

12 December 2020

10.1007/S10238-012-0201-X

Identifiers

DOI

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release_dwtoyb2kx5hdjdogavyukjuccq

10 September 2017

Fatcat ID

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