Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers. (Q39316736)

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7 February 2020

title

Characterization of the prostate cancer susceptibility gene KLF6 in human and mouse prostate cancers (English)

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7 February 2020

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12

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Carmela Ricciardelli

3

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Luke A. Selth

8

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Lisa M Butler

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author name string

Karen Chiam

1

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Natalie K Ryan

2

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Tanya K Day

4

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Grant Buchanan

5

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Aleksandra M Ochnik

6

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Krisna Murti

7

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Australian Prostate Cancer BioResource

9

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Wayne D Tilley

11

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publication date

10 July 2012

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volume

73

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issue

2

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page(s)

182-193

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Krüppel-like factors: three fingers in many pies

7 February 2020

cites work

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Krüppel-like transcription factors: a functional family

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The role of KLF6 and its splice variants in cancer therapy

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Krüppel cripples prostate cancer: KLF6 progress and prospects

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Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

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Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.

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Growth inhibitory effect of Krüppel-like factor 6 on human prostatic carcinoma and renal carcinoma cell lines

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KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3

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Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway

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KLF6, a candidate tumor suppressor gene mutated in prostate cancer

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KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

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Deletion, mutation, and loss of expression of KLF6 in human prostate cancer

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Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell lines

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Gene expression profiling predicts clinical outcome of prostate cancer

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Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

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Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma

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Suppression of glioblastoma tumorigenicity by the Kruppel-like transcription factor KLF6.

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Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer.

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Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer

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Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination.

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Kruppel-like factor 6 germ-line mutations are infrequent in Finnish hereditary prostate cancer

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KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations.

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Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

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Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development

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Identifiers

DOI

10.1002/PROS.22554

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22782870%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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