The Epstein-Barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells (Q39321358)

11 September 2017

The Epstein-Barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells (English)

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11 September 2017

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Timothy R Geiger

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11 September 2017

Jennifer M Martin

series ordinal

2

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11 September 2017

language of work or name

English

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publication date

20 September 2006

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80

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23

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11638-11650

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describes a project that uses

11 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1642610/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Mechanisms of type-I- and type-II-interferon-mediated signalling

11 September 2017

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Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells

11 September 2017

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11 September 2017

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11 September 2017

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11 September 2017

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Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells

11 September 2017

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A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response

11 September 2017

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CD40 and its viral mimic, LMP1: similar means to different ends

11 September 2017

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Intracellular signaling molecules activated by Epstein-Barr virus for induction of interferon regulatory factor 7.

11 September 2017

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Interferon regulatory factor 7 mediates activation of Tap-2 by Epstein-Barr virus latent membrane protein 1.

11 September 2017

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Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

11 September 2017

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Partial impairment of cytokine responses in Tyk2-deficient mice

11 September 2017

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Interferon regulatory factor 7 is induced by Epstein-Barr virus latent membrane protein 1

11 September 2017

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The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha

11 September 2017

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Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins

11 September 2017

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Interferon regulatory factor 2 represses the Epstein-Barr virus BamHI Q latency promoter in type III latency

11 September 2017

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Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor

11 September 2017

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Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

11 September 2017

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IRF-7, a new interferon regulatory factor associated with Epstein-Barr virus latency

11 September 2017

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Interferon-independent and -induced regulation of Epstein-Barr virus EBNA-1 gene transcription in Burkitt lymphoma.

11 September 2017

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Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation

11 September 2017

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Drosophila MCM protein complexes

11 September 2017

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Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation

11 September 2017

1 reference

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Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

11 September 2017

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Prevention of Epstein-Barr virus-induced B-cell outgrowth by interferon alpha

11 September 2017

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Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells

11 September 2017

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An Epstein-Barr virus transforming protein associates with vimentin in lymphocytes

11 September 2017

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Posttranslational processing of the Epstein-Barr virus-encoded p63/LMP protein

11 September 2017

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Cytoskeletal association of human alpha-interferon-receptor complexes in interferon-sensitive and -resistant lymphoblastoid cells

11 September 2017

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The transforming domain alone of the latent membrane protein of Epstein-Barr virus is toxic to cells when expressed at high levels

11 September 2017

1 reference

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Transformation by the oncogenic latent membrane protein correlates with its rapid turnover, membrane localization, and cytoskeletal association

11 September 2017

1 reference

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Epstein-Barr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes

11 September 2017

1 reference

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Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis

11 September 2017

1 reference

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Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphoma

14 September 2017

1 reference

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Latent membrane protein 1 of Epstein-Barr virus inhibits as well as stimulates gene expression

14 September 2017

1 reference

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The latent membrane protein 1 of Epstein-Barr virus (EBV) primes EBV latency cells for type I interferon production

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

High physiological levels of LMP1 result in phosphorylation of eIF2 alpha in Epstein-Barr virus-infected cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

Cutting edge: tyk2 is required for the induction and nuclear translocation of Daxx which regulates IFN-alpha-induced suppression of B lymphocyte formation.

14 September 2017

1 reference

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Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

The cytoplasmic amino-terminus of the Latent Membrane Protein-1 of Epstein-Barr Virus: relationship between transmembrane orientation and effector functions of the carboxy-terminus and transmembrane domain

14 September 2017

1 reference

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EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

Early detection of the lytic LMP-1 protein in EBV-infected B-cells suggests its presence in the virion

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

The latent membrane protein oncoprotein resembles growth factor receptors in the properties of its turnover

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

The transformation of adult but not newborn human lymphocytes by Epstein Barr virus and phytohemagglutinin is inhibited by interferon: the early suppression by T cells of Epstein Barr infection is mediated by interferon

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

Regulation of Epstein-Barr virus infection by recombinant interferons. Selected sensitivity to interferon-gamma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

Cytokine signaling: STATS in plasma membrane rafts

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

The Epstein-Barr virus nuclear antigen 2 (EBNA2), a protein required for B lymphocyte immortalization, induces the synthesis of type I interferon in Burkitt's lymphoma cell lines

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1642610

21 August 2018

Identifiers

DOI

10.1128/JVI.01570-06

1 reference

11 September 2017

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11 September 2017

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