Biological activities of an engineered tautomycetin analogue via disruption of tmcR-encoding hydroxylase in Streptomyces sp. CK4412. (Q39325225)

11 September 2017

title

Biological activities of an engineered tautomycetin analogue via disruption of tmcR-encoding hydroxylase in Streptomyces sp. CK4412. (English)

1 reference

Streptomyces griseochromogenes

11 September 2017

main subject

1 reference

inferred from

reverse claim

[(16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl] 3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoate

1 reference

Dongju Kim

1

1 reference

11 September 2017

Ji-Hye Nah

2

1 reference

11 September 2017

Si-Sun Choi

3

1 reference

11 September 2017

Hwa Sung Shin

4

1 reference

11 September 2017

David H Sherman

5

1 reference

11 September 2017

Eung-Soo Kim

6

1 reference

11 September 2017

publication date

26 June 2012

1 reference

full work available at URL

11 September 2017

https://academic.oup.com/jimb/article-pdf/39/10/1563/36803459/jimb1563.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1007/s10295-012-1157-2?email=unpaywall_01@example.com

published in

Journal of Industrial Microbiology & Biotechnology

1 reference

11 September 2017

volume

39

1 reference

11 September 2017

issue

10

1 reference

11 September 2017

page(s)

1563-1568

1 reference

https://api.unpaywall.org/v2/10.1007/s10295-012-1157-2?email=unpaywall_01@example.com

11 September 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

inferred from online access status

cites work

Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Molecular characterization of cytochrome P450 genes in the polycyclic aromatic hydrocarbon degrading Mycobacterium vanbaalenii PYR-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Identification of TmcN as a pathway-specific positive regulator of tautomycetin biosynthesis in Streptomyces sp. CK4412.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Tautomycetin inhibits growth of colorectal cancer cells through p21cip/WAF1 induction via the extracellular signal-regulated kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Characterization of the tautomycetin biosynthetic gene cluster from Streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

SHP2 is a target of the immunosuppressant tautomycetin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Immunosuppressive effects of tautomycetin in vivo and in vitro via T cell-specific apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

Functional characterization of ttnI completing the tailoring steps for tautomycetin biosynthesis in Streptomyces griseochromogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-012-1157-2

A new antibiotic, tautomycetin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22733296

12 December 2020

inferred from PubMed ID database lookup

Evaluation of the fluorometric protein phosphatase inhibition assay in the determination of okadaic acid in mussels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22733296

12 December 2020

inferred from PubMed ID database lookup

Identification and characterization of wblA-dependent tmcT regulation during tautomycetin biosynthesis in Streptomyces sp. CK4412

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22733296

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10295-012-1157-2

1 reference

release_zoep7kh5tbdgzphwdjrc6yzi2m

11 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zoep7kh5tbdgzphwdjrc6yzi2m

24 November 2022

mapped directly with Wikidata item

1 reference