Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation (Q39333626)

11 September 2017

title

Semaphorin 3A elevates endothelial cell permeability through PP2A inactivation (English)

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11 September 2017

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Armelle Le Guelte

1

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Lucas Treps

object named as

Lucas Treps

4

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author name string

Eva-Maria Galan-Moya

2

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11 September 2017

Julie Dwyer

3

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11 September 2017

Garance Kettler

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11 September 2017

Jagoda K Hebda

6

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11 September 2017

Sonia Dubois

7

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11 September 2017

Cedric Auffray

8

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11 September 2017

Herve Chneiweiss

9

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11 September 2017

Nicolas Bidere

10

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11 September 2017

Julie Gavard

11

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11 September 2017

Julie Gavard

12

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11 September 2017

language of work or name

English

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publication date

8 June 2012

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11 September 2017

published in

Journal of Cell Science

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11 September 2017

volume

125

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11 September 2017

issue

Pt 17

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11 September 2017

page(s)

4137-4146

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Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor

11 September 2017

cites work

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Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models

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Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model

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VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

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Role of class 3 semaphorins and their receptors in tumor growth and angiogenesis

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Breaking the VE-cadherin bonds.

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VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

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Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

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Semaphorin-3A and semaphorin-3F work together to repel endothelial cells and to inhibit their survival by induction of apoptosis

21 January 2018

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Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A

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Jumping the barrier: VE-cadherin, VEGF and other angiogenic modifiers in cancer.

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Caveolin-1-deficient mice have increased tumor microvascular permeability, angiogenesis, and growth.

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Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice

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The FGF system has a key role in regulating vascular integrity

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VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

21 January 2018

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VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.

21 January 2018

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Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex

21 January 2018

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CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors

21 January 2018

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Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

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Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.

21 January 2018

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Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

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Semaphorins and tumor angiogenesis.

21 January 2018

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21 January 2018

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Protein phosphatase 2A: the Trojan Horse of cellular signaling

21 January 2018

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A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients

21 January 2018

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p21-activated kinase regulates endothelial permeability through modulation of contractility.

21 January 2018

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Induction of E-cadherin endocytosis by loss of protein phosphatase 2A expression in human breast cancers

21 January 2018

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Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy

21 January 2018

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Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.

21 January 2018

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Rac1-induced cell migration requires membrane recruitment of the nuclear oncogene SET

21 January 2018

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Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor.

21 January 2018

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Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player

21 January 2018

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21 January 2018

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Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

21 January 2018

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Blood-brain barrier-specific properties of a human adult brain endothelial cell line

21 January 2018

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Multiple pathways regulated by the tumor suppressor PP2A in transformation

21 January 2018

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Protein phosphatase 2A interacts with the Src kinase substrate p130(CAS)

21 January 2018

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21 January 2018

Identifiers

DOI

10.1242/JCS.108282

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11 September 2017

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