Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells (Q39338173)

11 September 2017

Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells (English)

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11 September 2017

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Anna Pfenniger

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11 September 2017

Cindy Wong

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11 September 2017

Esther Sutter

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11 September 2017

Simon Cuhlmann

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11 September 2017

Sylvie Dunoyer-Geindre

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11 September 2017

François Mach

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11 September 2017

Anton J Horrevoets

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11 September 2017

Paul C Evans

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11 September 2017

Rob Krams

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11 September 2017

Brenda R Kwak

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11 September 2017

language of work or name

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29 May 2012

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Journal of Molecular and Cellular Cardiology

11 September 2017

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11 September 2017

53

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11 September 2017

2

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11 September 2017

299-309

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The immune system in atherosclerosis

11 September 2017

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Pathology of atherosclerosis and stenting

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Shear stress biology of the endothelium

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Molecular mechanisms of the vascular responses to haemodynamic forces

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Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress.

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KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium

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Plasma membrane channels formed by connexins: their regulation and functions.

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Beyond the gap: functions of unpaired connexon channels

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Connexin channel permeability to cytoplasmic molecules

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Connexin37: a potential modifier gene of inflammatory disease.

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Altered pattern of vascular connexin expression in atherosclerotic plaques

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Connexin37 protects against atherosclerosis by regulating monocyte adhesion

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Differential endothelial gap junction expression in venous vessels exposed to different hemodynamics.

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Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique.

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Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

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Gap junction protein Cx37 interacts with endothelial nitric oxide synthase in endothelial cells.

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Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

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Inhibition of endothelial wound repair by dominant negative connexin inhibitors.

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KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation

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Statins exert endothelial atheroprotective effects via the KLF2 transcription factor

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Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cells

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Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization.

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Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells

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Unexpected role for the human Cx37 C1019T polymorphism in tumour cell proliferation

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Connexin 37 profoundly slows cell cycle progression in rat insulinoma cells

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Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2.

7 January 2021

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Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed

7 January 2021

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Regulation of vascular connexin43 gene expression by mechanical loads

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Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro

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Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells

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Transcriptional remodeling of ion channel subunits by flow adaptation in human coronary artery endothelial cells.

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Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress

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Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal

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Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.

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Endothelial connexin 37, connexin 40, and connexin 43 respond uniquely to substrate and shear stress.

7 January 2021

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Flow regulates intercellular communication in HAEC by assembling functional Cx40 and Cx37 gap junctional channels.

7 January 2021

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Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2.

7 January 2021

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KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium

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Kruppel-like factor 2 (KLF2) regulates endothelial thrombotic function

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KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells

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Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells

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Heterogeneity of [Ca(2+)](i) signaling in intact rat aortic endothelium

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Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion

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Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress

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7 January 2021

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DOI

10.1016/J.YJMCC.2012.05.011

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11 September 2017

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