ADAM10 overexpression confers resistance to doxorubicin-induced apoptosis in hepatocellular carcinoma (Q39348959)

11 September 2017

title

ADAM10 overexpression confers resistance to doxorubicin-induced apoptosis in hepatocellular carcinoma (English)

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11 September 2017

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Cheng-lin Yang

1

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11 September 2017

Feng-qin Jiang

series ordinal

2

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11 September 2017

Feng Xu

series ordinal

3

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11 September 2017

Gui-xing Jiang

series ordinal

4

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11 September 2017

publication date

13 May 2012

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11 September 2017

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11 September 2017

volume

33

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11 September 2017

issue

5

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11 September 2017

page(s)

1535-1541

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https://scigraph.springernature.com/pub.10.1007/s13277-012-0405-4

11 September 2017

exact match

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cites work

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Transarterial chemoembolization can be safely performed in patients with hepatocellular carcinoma invading the main portal vein and may improve the overall survival.

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Active metalloproteases of the A Disintegrin and Metalloprotease (ADAM) family: biological function and structure.

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ADAM10 is upregulated in melanoma metastasis compared with primary melanoma.

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Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma

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Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.

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Inhibiting adenoid cystic carcinoma cells growth and metastasis by blocking the expression of ADAM 10 using RNA interference

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The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells

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The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.

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Emerging roles of caspase-3 in apoptosis

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Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.

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Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol

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Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression

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The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

21 January 2018

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Chemotherapy-induced activation of ADAM-17: a novel mechanism of drug resistance in colorectal cancer

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ADAM15 exerts an antiapoptotic effect on osteoarthritic chondrocytes via up-regulation of the X-linked inhibitor of apoptosis

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The metalloproteinase ADAM-12 regulates bronchial epithelial cell proliferation and apoptosis.

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A role for ADAM12 in breast tumor progression and stromal cell apoptosis.

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MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib

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Sorafenib in advanced hepatocellular carcinoma

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Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction.

21 January 2018

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HBx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of Mcl-1 protein via caspase-3 cascade

21 January 2018

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Bufalin and cinobufagin induce apoptosis of human hepatocellular carcinoma cells via Fas- and mitochondria-mediated pathways

21 January 2018

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Telomerase-dependent virotherapy overcomes resistance of hepatocellular carcinomas against chemotherapy and tumor necrosis factor-related apoptosis-inducing ligand by elimination of Mcl-1.

21 January 2018

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Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

21 January 2018

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Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells

21 January 2018

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Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway

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Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis

21 January 2018

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Akt-mediated eminent expression of c-FLIP and Mcl-1 confers acquired resistance to TRAIL-induced cytotoxicity to lung cancer cells

21 January 2018

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Comparison of conventional transarterial chemoembolization (TACE) and chemoembolization with doxorubicin drug eluting beads (DEB) for unresectable hepatocelluar carcinoma (HCC)

21 January 2018

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12 December 2020

Drug-eluting bead loaded with doxorubicin versus conventional Lipiodol-based transarterial chemoembolization in the treatment of hepatocellular carcinoma: a case-control study of Asian patients

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12 December 2020

ADAM 10 is associated with gastric cancer progression and prognosis of patients

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12 December 2020

Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma.

1 reference

12 December 2020

Expression of A disintegrin and metalloprotease 10 in pancreatic carcinoma

1 reference

12 December 2020

Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway

1 reference

12 December 2020

10.1007/S13277-012-0405-4

Identifiers

DOI

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11 September 2017

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