AID-driven deletion causes immunoglobulin heavy chain locus suicide recombination in B cells. (Q39357606)

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30 January 2020

title

AID-driven deletion causes immunoglobulin heavy chain locus suicide recombination in B cells (English)

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30 January 2020

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1

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30 January 2020

Laurent Delpy

6

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30 January 2020

Eric Pinaud

8

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30 January 2020

Michel Cogné

9

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30 January 2020

author name string

Brice Laffleur

2

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30 January 2020

Nicolas Denis-Lagache

3

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30 January 2020

Jeanne Cook-Moreau

4

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30 January 2020

Aurélien Tinguely

5

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30 January 2020

Yves Denizot

7

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language of work or name

English

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publication date

26 April 2012

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30 January 2020

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30 January 2020

volume

336

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30 January 2020

issue

6083

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30 January 2020

page(s)

931-934

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Control systems and decision making for antibody production.

30 January 2020

cites work

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The IgH locus 3' regulatory region: pulling the strings from behind

21 January 2018

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The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells

21 January 2018

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Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus

21 January 2018

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Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites

21 January 2018

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Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region

21 January 2018

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Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

21 January 2018

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In vivo redundant function of the 3' IgH regulatory element HS3b in the mouse.

21 January 2018

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Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes.

21 January 2018

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S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase

21 January 2018

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Evidence for physical interaction between the immunoglobulin heavy chain variable region and the 3' regulatory region

21 January 2018

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Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells

21 January 2018

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Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.

21 January 2018

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Palindromic structure of the IgH 3'locus control region.

21 January 2018

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Comparative analysis of human and mouse 3' Igh regulatory regions identifies distinctive structural features

21 January 2018

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Identification of a homolog of the C alpha 3'/hs3 enhancer and of an allelic variant of the 3'IgH/hs1,2 enhancer downstream of the human immunoglobulin alpha 1 gene.

21 January 2018

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Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

21 January 2018

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Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

21 January 2018

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Two levels of protection for the B cell genome during somatic hypermutation.

21 January 2018

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Mechanism and regulation of class switch recombination

21 January 2018

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Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.

21 January 2018

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Widespread transcription at neuronal activity-regulated enhancers

21 January 2018

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High-resolution profiling of gammaH2AX around DNA double strand breaks in the mammalian genome.

21 January 2018

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Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 January 2018

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A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs

21 January 2018

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