Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease (Q39360363)

11 September 2017

Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease (English)

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Niemann–Pick disease, type C

11 September 2017

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Mary Carmen Vázquez

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11 September 2017

Pablo Martínez

2

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11 September 2017

Alejandra R Alvarez

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11 September 2017

Mauricio González

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11 September 2017

Silvana Zanlungo

5

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11 September 2017

17 April 2012

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11 September 2017

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11 September 2017

25

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4

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777-786

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https://scigraph.springernature.com/pub.10.1007/s10534-012-9546-6

11 September 2017

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Relevance of Niemann-Pick type C1 protein expression in controlling plasma cholesterol and biliary lipid secretion in mice

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Metals in Alzheimer's and Parkinson's diseases

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ATP7B mediates vesicular sequestration of copper: insight into biliary copper excretion

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Copper increases the damage to DNA and proteins caused by reactive oxygen species.

21 January 2018

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21 January 2018

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Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells

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NH2-terminal signals in ATP7B Cu-ATPase mediate its Cu-dependent anterograde traffic in polarized hepatic cells

21 January 2018

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Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons

21 January 2018

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Increased cholesterol in plasma in a young man during experimental copper depletion

21 January 2018

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Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport

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Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons.

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Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

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Beneficial effects of anti-inflammatory therapy in a mouse model of Niemann-Pick disease type C1.

21 January 2018

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Biliary excretion of copper in LEC rat after introduction of copper transporting P-type ATPase, ATP7B.

21 January 2018

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Alteration of gene expression profile in Niemann-Pick type C mice correlates with tissue damage and oxidative stress

21 January 2018

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Oxidative stress-mediated hepatotoxicity of iron and copper: role of Kupffer cells

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Telomerase immortalization upregulates Rab9 expression and restores LDL cholesterol egress from Niemann-Pick C1 late endosomes

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Recommendations on the diagnosis and management of Niemann-Pick disease type C.

21 January 2018

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Niemann-Pick C1 protein transports copper to the secretory compartment from late endosomes where ATP7B resides

21 January 2018

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Copper incorporation into ceruloplasmin is regulated by Niemann-Pick C1 protein.

21 January 2018

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The mannose 6-phosphate receptor and the biogenesis of lysosomes

21 January 2018

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Lysosomal vitamin E accumulation in Niemann–Pick type C disease

21 January 2018

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10.1007/S10534-012-9546-6

21 January 2018

Identifiers

DOI

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11 September 2017

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