Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A. (Q39363776)

11 September 2017

title

Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A. (English)

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11 September 2017

1 reference

I P Foskolou

1

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11 September 2017

D Stellas

2

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11 September 2017

I Rozani

3

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11 September 2017

M D Lavigne

4

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11 September 2017

P K Politis

5

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11 September 2017

language of work or name

English

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publication date

16 April 2012

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11 September 2017

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11 September 2017

volume

32

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11 September 2017

issue

8

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11 September 2017

page(s)

947-960

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https://api.crossref.org/works/10.1038%2FONC.2012.129

11 September 2017

1 reference

High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Homeobox transcription factor Prox1 in sympathetic ganglia of vertebrate embryos: correlation with human stage 4s neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 regulates the notch1-mediated inhibition of neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Notch1 expression predicts an unfavorable prognosis and serves as a therapeutic target of patients with neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 maintains muscle structure and growth in the developing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Hepatocyte migration during liver development requires Prox1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 function is crucial for mouse lens-fibre elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Altered regulation of Prox1-gene-expression in liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Notch signalling in vertebrate neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Progenitor cell maintenance and neurogenesis in sympathetic ganglia involves Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Regulation of the lymphatic endothelial cell cycle by the PROX1 homeodomain protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

p53 downregulates expression of the G1/S cell cycle phosphatase Cdc25A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Cdc25 phosphatases are required for timely assembly of CDK1-cyclin B at the G2/M transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 is a marker of ectodermal placodes, endodermal compartments, lymphatic endothelium and lymphangioblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Roles for MSI2 and PROX1 in hematopoietic stem cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Transcriptional factor Prox1 plays an essential role in the antiproliferative action of interferon-γ in esophageal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

A transient expression of Prospero promotes cell cycle exit of Drosophila postembryonic neurons through the regulation of Dacapo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Transcription of the Drosophila CKI gene dacapo is regulated by a modular array of cis-regulatory sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Neural stem cell transcriptional networks highlight genes essential for nervous system development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prospero maintains the mitotic potential of glial precursors enabling them to respond to neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Angiogenesis in a human neuroblastoma xenograft model: mechanisms and inhibition by tumour-derived interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 expression is negatively regulated by miR-181 in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Differential patterns of microRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

BM88 is a dual function molecule inducing cell cycle exit and neuronal differentiation of neuroblastoma cells via cyclin D1 down-regulation and retinoblastoma protein hypophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

BM88/Cend1 is involved in histone deacetylase inhibition-mediated growth arrest and differentiation of neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

BM88/CEND1 coordinates cell cycle exit and differentiation of neuronal precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Cell cycle regulation by the Cdc25 phosphatase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Cell cycle checkpoints and their inactivation in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Targets of cyclin-dependent protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Prox1 function is required for the development of the murine lymphatic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Sox1 maintains the undifferentiated state of cortical neural progenitor cells via the suppression of Prox1-mediated cell cycle exit and neurogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

Low-dose interferon-gamma-producing human neuroblastoma cells show reduced proliferation and delayed tumorigenicity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.129

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.129

1 reference

11 September 2017

1 reference