Determinants within gp120 and gp41 contribute to CD4 independence of SIV Envs (Q39370712)

11 September 2017

title

Determinants within gp120 and gp41 contribute to CD4 independence of SIV Envs (English)

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11 September 2017

3

Theodore C Pierson

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11 September 2017

Bridget A Puffer

1

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11 September 2017

Louis A Altamura

series ordinal

2

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11 September 2017

Robert W Doms

series ordinal

4

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11 September 2017

language of work or name

English

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publication date

1 September 2004

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11 September 2017

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11 September 2017

volume

327

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11 September 2017

issue

1

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11 September 2017

page(s)

16-25

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Analysis of envelope changes acquired by SIVmac239 during neuroadaption in rhesus macaques

11 September 2017

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Unique Pattern of Convergent Envelope Evolution in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques: Association with CD4-Independent Usage of CCR5

7 January 2021

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Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor

7 January 2021

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Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein

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Truncation of the cytoplasmic domain induces exposure of conserved regions in the ectodomain of human immunodeficiency virus type 1 envelope protein

7 January 2021

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CD4-independent infection by HIV-2 is mediated by fusin/CXCR4.

7 January 2021

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Capture of an early fusion-active conformation of HIV-1 gp41

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Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

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Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

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CD4-independent use of Rhesus CCR5 by human immunodeficiency virus Type 2 implicates an electrostatic interaction between the CCR5 N terminus and the gp120 C4 domain

7 January 2021

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Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4

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7 January 2021

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CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity

7 January 2021

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7 January 2021

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Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

7 January 2021

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The intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques.

7 January 2021

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The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter]

7 January 2021

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A variable region 3 (V3) mutation determines a global neutralization phenotype and CD4-independent infectivity of a human immunodeficiency virus type 1 envelope associated with a broadly cross-reactive, primary virus-neutralizing antibody response

7 January 2021

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7 January 2021

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Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein

7 January 2021

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Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins

7 January 2021

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7 January 2021

Functional dissection of CCR5 coreceptor function through the use of CD4-independent simian immunodeficiency virus strains

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7 January 2021

Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity

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7 January 2021

Restricted replication of simian immunodeficiency virus strain 239 in macrophages is determined by env but is not due to restricted entry

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7 January 2021

The CD4-independent tropism of human immunodeficiency virus type 2 involves several regions of the envelope protein and correlates with a reduced activation threshold for envelope-mediated fusion

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7 January 2021

Primary human immunodeficiency virus type 2 (HIV-2) isolates infect CD4-negative cells via CCR5 and CXCR4: comparison with HIV-1 and simian immunodeficiency virus and relevance to cell tropism in vivo

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7 January 2021

Conformational changes induced in the envelope glycoproteins of the human and simian immunodeficiency viruses by soluble receptor binding

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7 January 2021

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

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7 January 2021

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Identifiers

DOI

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11 September 2017

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