Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line (Q39385587)

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English	Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line	scientific article

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scholarly article

1 reference

Europe PubMed Central

11 September 2017

Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line (English)

1 reference

Europe PubMed Central

11 September 2017

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author name string

Keiko Ishihara

1

1 reference

Europe PubMed Central

11 September 2017

Tsuguhisa Ehara

2

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Europe PubMed Central

11 September 2017

language of work or name

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publication date

14 January 2004

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Europe PubMed Central

11 September 2017

number of pages

18

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Journal of Physiology

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Europe PubMed Central

11 September 2017

556

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Europe PubMed Central

11 September 2017

Pt 1

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Europe PubMed Central

11 September 2017

61-78

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Europe PubMed Central

11 September 2017

Role of individual ionic current systems in ventricular cells hypothesized by a model study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Voltage-dependent gating and block by internal spermine of the murine inwardly rectifying K+ channel, Kir2.1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

IRK1 inward rectifier K(+) channels exhibit no intrinsic rectification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Constitutively active and G-protein coupled inward rectifier K+ channels: Kir2.0 and Kir3.0.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Spermine block of the strong inward rectifier potassium channel Kir2.1: dual roles of surface charge screening and pore block

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Inward rectifier K(+) current under physiological cytoplasmic conditions in guinea-pig cardiac ventricular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Unitary conductance variation in Kir2.1 and in cardiac inward rectifier potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

The consequences of disrupting cardiac inwardly rectifying K(+) current (I(K1)) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Inward rectifiers in the heart: an update on I(K1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Pore block versus intrinsic gating in the mechanism of inward rectification in strongly rectifying IRK1 channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Mechanism of IRK1 channel block by intracellular polyamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Architecture of a K+ channel inner pore revealed by stoichiometric covalent modification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

A repolarization-induced transient increase in the outward current of the inward rectifier K+ channel in guinea-pig cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Inhibition of rat ventricular IK1 with antisense oligonucleotides targeted to Kir2.1 mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Time-dependent outward currents through the inward rectifier potassium channel IRK1. The role of weak blocking molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

The tetravalent organic cation spermine causes the gating of the IRK1 channel expressed in murine fibroblast cells

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

https://pubmed.ncbi.nlm.nih.gov/14724206

12 December 2020

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inferred from PubMed ID database lookup

Inward rectification of the IRK1 channel expressed in Xenopus oocytes: effects of intracellular pH reveal an intrinsic gating mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Maternal and zygotic expression of mRNA for S-adenosylmethionine decarboxylase and its relevance to the unique polyamine composition in Xenopus oocytes and embryos.

1 reference

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30 August 2018

The mechanism of inward rectification of potassium channels: "long-pore plugging" by cytoplasmic polyamines

1 reference

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30 August 2018

C-terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

The intrinsic gating of inward rectifier K+ channels expressed from the murine IRK1 gene depends on voltage, K+ and Mg2+

1 reference

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30 August 2018

Gating of inwardly rectifying K+ channels localized to a single negatively charged residue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Spermine and spermidine as gating molecules for inward rectifier K+ channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Strong voltage-dependent inward rectification of inward rectifier K+ channels is caused by intracellular spermine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Primary structure and functional expression of a mouse inward rectifier potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

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30 August 2018

Isolation of calcium current and its sensitivity to monovalent cations in dialysed ventricular cells of guinea-pig

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30 August 2018

Ionic Blockage of Sodium Channels in Nerve

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30 August 2018

Open-state substructure of inwardly rectifying potassium channels revealed by magnesium block in guinea-pig heart cells

1 reference

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30 August 2018

Activation properties of the inward-rectifying potassium channel on mammalian heart cells

1 reference

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30 August 2018

Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions

1 reference

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30 August 2018

Ohmic conductance through the inwardly rectifying K channel and blocking by internal Mg2+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1664885

30 August 2018

Voltage-dependent activation of the inward-rectifier potassium channel in the ventricular cell membrane of guinea-pig heart

1 reference

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30 August 2018

Intrinsic gating of inward rectifier in bovine pulmonary artery endothelial cells in the presence or absence of internal Mg2+.

1 reference

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The mechanism of rectification of iK1 in canine Purkinje myocytes

1 reference

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

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Potassium current and the effect of cesium on this current during anomalous rectification of the egg cell membrane of a starfish

1 reference

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Inward rectification in frog skeletal muscle fibres and its dependence on membrane potential and external potassium

1 reference

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Comparison of potassium currents in rabbit atrial and ventricular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Mg2+ block and intrinsic gating underlying inward rectification of the K+ current in guinea-pig cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between the inhibition of cell growth by accumulated polyamines and the decrease of magnesium and ATP

1 reference

https://pubmed.ncbi.nlm.nih.gov/14724206

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2003.055434

1 reference

Europe PubMed Central

11 September 2017

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1 reference

Europe PubMed Central

11 September 2017

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