Global DNA methylation levels are modulated by mitochondrial DNA variants (Q39396837)

11 September 2017

Global DNA methylation levels are modulated by mitochondrial DNA variants (English)

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11 September 2017

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Dina Bellizzi

1

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11 September 2017

Patrizia D'Aquila

2

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11 September 2017

Marco Giordano

3

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11 September 2017

Alberto Montesanto

4

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11 September 2017

Giuseppe Passarino

5

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11 September 2017

1 February 2012

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11 September 2017

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11 September 2017

4

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11 September 2017

17-27

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11 September 2017

1

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describes a project that uses

11 September 2017

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Mitochondria and reactive oxygen species

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Reactive oxygen species, cellular redox systems, and apoptosis

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA and human evolution

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA variation in human populations and implications for detection of mitochondrial DNA mutations of pathological significance

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Harvesting the fruit of the human mtDNA tree

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Human mtDNA haplogroups associated with high or reduced spermatozoa motility

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA involvement in human longevity

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

A mitochondrial etiology of neurodegenerative diseases: evidence from Parkinson's disease.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial haplogroups associated with lifestyle-related diseases and longevity in the Japanese population

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Polymorphisms in the mitochondrial DNA control region and frailty in older adults

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial haplogroups associated with Japanese centenarians, Alzheimer's patients, Parkinson's patients, type 2 diabetic patients and healthy non-obese young males.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

No evidence for an mtDNA role in sperm motility: data from complete sequencing of asthenozoospermic males

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA haplogroups do not influence the Huntington's disease phenotype

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Is there a primary role of the mitochondrial genome in Alzheimer's disease?

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Human mitochondrial variants influence on oxygen consumption

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Impact of the mitochondrial genetic background in complex III deficiency

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA variation in human metabolic rate and energy expenditure

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Differences in reactive oxygen species production explain the phenotypes associated with common mouse mitochondrial DNA variants

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Natural selection shaped regional mtDNA variation in humans

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Evidence for adaptive selection acting on the tRNA and rRNA genes of human mitochondrial DNA.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Testing the adaptive selection of human mtDNA haplogroups: an experimental bioenergetics approach

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Platelet-mediated transformation of human mitochondrial DNA-less cells

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Relationships between mitochondrial DNA subhaplogroups and intracellular calcium dynamics.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA variability modulates mRNA and intra-mitochondrial protein levels of HSP60 and HSP75: experimental evidence from cybrid lines

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

The coordination of nuclear and mitochondrial communication during aging and calorie restriction

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Gene expression pattern in transmitochondrial cytoplasmic hybrid cells harboring type 2 diabetes-associated mitochondrial DNA haplogroups

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Specific interaction of methionine adenosyltransferase with free radicals.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial control of epigenetics

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondria, bioenergetics, and the epigenome in eukaryotic and human evolution

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Energetics, epigenetics, mitochondrial genetics

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

DNA adduct 8-hydroxyl-2'-deoxyguanosine (8-hydroxyguanine) affects function of human DNA methyltransferase

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Bioenergetics and the epigenome: interface between the environment and genes in common diseases

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

A novel role for mitochondria in regulating epigenetic modification in the nucleus

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

To grow old in southern Italy: a comprehensive description of the old and oldest old in Calabria.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

A high-throughput and sensitive method to measure global DNA methylation: application in lung cancer

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial-nuclear communications

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Nuclear-mitochondrial interaction.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Population screening for association of mitochondrial haplogroups BM, J, K and M with multiple sclerosis: interrelation between haplogroup J and MS in Persian patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Haplogroup effects and recombination of mitochondrial DNA: novel clues from the analysis of Leber hereditary optic neuropathy pedigrees.

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Clinical expression of Leber hereditary optic neuropathy is affected by the mitochondrial DNA-haplogroup background

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Effects of purifying and adaptive selection on regional variation in human mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial DNA haplogroups and type 2 diabetes: a study of 897 cases and 1010 controls

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial function, mitochondrial DNA and ageing: a reappraisal.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Inhibition of human methionine adenosyltransferase 1A transcription by coding region methylation

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

ATP-dependent chromatin remodeling: genetics, genomics and mechanisms

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Cloning and functional characterization of the 5'-flanking region of human methionine adenosyltransferase 1A gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.109

Mitochondrial nuclear receptors and transcription factors: who's minding the cell?

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Common and cell type-specific responses of human cells to mitochondrial dysfunction

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

Association of mitochondrial haplogroup J and mtDNA oxidative damage in two different North Spain elderly populations

21 January 2018

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https://api.crossref.org/works/10.2217%2FEPI.11.109

21 January 2018

Identifiers

DOI

10.2217/EPI.11.109

1 reference

11 September 2017

1 reference