Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality (Q39410275)

11 September 2017

title

Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality (English)

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immunophilin FK506 binding protein FKBP12, putative

11 September 2017

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5 February 2019

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Alessandro Rossi

1

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11 September 2017

Livia Pica-Mattoccia

series ordinal

2

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11 September 2017

Donato Cioli

series ordinal

3

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11 September 2017

Mo-Quen Klinkert

series ordinal

4

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11 September 2017

publication date

1 November 2002

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Molecular and Biochemical Parasitology

11 September 2017

published in

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11 September 2017

volume

125

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11 September 2017

issue

1-2

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11 September 2017

page(s)

1-9

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Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action

11 September 2017

cites work

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Roles of peptidyl-prolyl cis-trans isomerase and calcineurin in the mechanisms of antimalarial action of cyclosporin A, FK506, and rapamycin

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Cyclophilin: a specific cytosolic binding protein for cyclosporin A

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7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

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7 January 2021

Sequence diversification of the FK506-binding proteins in several different genomes

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7 January 2021

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

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7 January 2021

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

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7 January 2021

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1 reference

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7 January 2021

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

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7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

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7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

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7 January 2021

Calcineurin is required for virulence of Cryptococcus neoformans

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7 January 2021

Praziquantel: is there real resistance and are there alternatives?

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7 January 2021

Characterization of a Schistosoma mansoni cDNA encoding a B-like cyclophilin and its expression in Escherichia coli.

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7 January 2021

Cyclosporins: lack of correlation between antischistosomal properties and inhibition of cyclophilin isomerase activity

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7 January 2021

Assay of Schistosoma mansoni calcineurin phosphatase activity and assessment of its role in parasite survival

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7 January 2021

Molecular cloning of Schistosoma mansoni calcineurin subunits and immunolocalization to the excretory system

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7 January 2021

A method for producing specific antisera with small doses of immunogen

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7 January 2021

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

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7 January 2021

PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae

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7 January 2021

Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae

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7 January 2021

Schistosoma mansoni Ca2+-ATPase SMA2 restores viability to yeast Ca2+-ATPase-deficient strains and functions in calcineurin-mediated Ca2+ tolerance

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7 January 2021

Schistosoma mansoni: characterization of p50, an immunophilin.

1 reference

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7 January 2021

Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex

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7 January 2021

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

1 reference

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7 January 2021

FK506 binding protein mutational analysis. Defining the surface residue contributions to stability of the calcineurin co-complex

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7 January 2021

TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin.

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7 January 2021

10.1016/S0166-6851(02)00207-4

Identifiers

DOI

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11 September 2017

1 reference