MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway. (Q39420283)

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English	MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway.	scientific article

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26 February 2020

MicroRNA miR-491-5p targeting both TP53 and Bcl-XL induces cell apoptosis in SW1990 pancreatic cancer cells through mitochondria mediated pathway (English)

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26 February 2020

apoptotic process

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pancreatic cancer

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author name string

Rong Guo

1

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26 February 2020

Yi Wang

2

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26 February 2020

Wei-Ye Shi

3

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26 February 2020

Bin Liu

4

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26 February 2020

Sheng-Qi Hou

5

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26 February 2020

Li Liu

6

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26 February 2020

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11 December 2012

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26 February 2020

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26 February 2020

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26 February 2020

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26 February 2020

14733-14747

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26 February 2020

copyright license

Creative Commons Attribution 4.0 International

11 December 2012

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April 2022 Public Data File from Crossref

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MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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The CD95(APO-1/Fas) DISC and beyond

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Functional and biological analysis of Bcl-xL expression in human osteosarcoma

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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MicroRNA expression profiles associated with pancreatic adenocarcinoma and ampullary adenocarcinoma

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung

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12 December 2020

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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https://pubmed.ncbi.nlm.nih.gov/23519249

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Cancer statistics, 2010

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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MicroRNA profiling of diagnostic needle aspirates from patients with pancreatic cancer

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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The cell growth suppressor, mir-126, targets IRS-1

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Cytochrome c: functions beyond respiration

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Role of phosphatidylinositol 3-kinase and specific protein kinase B isoforms in the suppression of apoptosis mediated by the Abelson protein-tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

based on heuristic

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MicroRNA functional network in pancreatic cancer: from biology to biomarkers of disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Bcl-x(L) and Akt cooperate to promote leukemogenesis in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Epidemiology and risk factors for pancreatic cancer.

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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MicroRNAs as oncogenes and tumor suppressors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Rational design of new class of BH3-mimetics as inhibitors of the Bcl-xL protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Fas ligand-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Apoptosis: a review of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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A review on the role of microRNA in biology, diagnosis, and treatment of pancreatic adenocarcinoma

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Expression of microRNAs in patients with pancreatic cancer and its prognostic significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

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Pancreatic cancer: epidemiology and risk factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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The BCL-2 protein family: opposing activities that mediate cell death

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https://pubmed.ncbi.nlm.nih.gov/23519249

12 December 2020

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Overexpression of Bcl-x(L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model

1 reference

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12 December 2020

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Identifiers

10.3390/MOLECULES171214733

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26 February 2020

release_hf6jyg66uveofgcgabecwewcve

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https://api.fatcat.wiki/v0/release/hf6jyg66uveofgcgabecwewcve

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

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26 February 2020

1 reference

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26 February 2020

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