The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation (Q39437383)

12 September 2017

The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation (English)

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12 September 2017

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E Rao

1

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12 September 2017

C Jiang

2

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12 September 2017

M Ji

3

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12 September 2017

X Huang

4

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12 September 2017

J Iqbal

5

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12 September 2017

G Lenz

6

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12 September 2017

G Wright

7

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12 September 2017

L M Staudt

8

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12 September 2017

Y Zhao

9

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12 September 2017

T W McKeithan

10

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12 September 2017

W C Chan

11

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12 September 2017

K Fu

12

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12 September 2017

25 November 2011

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12 September 2017

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12 September 2017

26

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12 September 2017

5

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12 September 2017

1064-1072

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https://scigraph.springernature.com/pub.10.1038/leu.2011.305

12 September 2017

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Mantle cell lymphoma: presenting features, response to therapy, and prognostic factors.

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Clustering of breakpoints on chromosome 11 in human B-cell neoplasms with the t(11 ; 14) chromosome translocation

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Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice.

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7 January 2021

Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature

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7 January 2021

Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma

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7 January 2021

A microRNA polycistron as a potential human oncogene

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7 January 2021

A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

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7 January 2021

c-Myc-regulated microRNAs modulate E2F1 expression

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7 January 2021

Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster

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7 January 2021

Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells

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7 January 2021

MicroRNA expression, chromosomal alterations, and immunoglobulin variable heavy chain hypermutations in Mantle cell lymphomas.

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7 January 2021

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

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7 January 2021

Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage

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7 January 2021

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

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7 January 2021

Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.

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7 January 2021

Proteomic analysis of mantle-cell lymphoma by protein microarray

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7 January 2021

Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma

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https://api.crossref.org/works/10.1038%2FLEU.2011.305

7 January 2021

Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia

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https://api.crossref.org/works/10.1038%2FLEU.2011.305

7 January 2021

miR-19 is a key oncogenic component of mir-17-92

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https://api.crossref.org/works/10.1038%2FLEU.2011.305

7 January 2021

The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma

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7 January 2021

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

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7 January 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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Prediction of mammalian microRNA targets

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MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

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7 January 2021

A microRNA cluster as a target of genomic amplification in malignant lymphoma.

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7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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7 January 2021

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

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7 January 2021

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms

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https://api.crossref.org/works/10.1038%2FLEU.2011.305

7 January 2021

PHLPPing it off: phosphatases get in the Akt

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7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

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7 January 2021

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

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7 January 2021

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

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7 January 2021

Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM.

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7 January 2021

Bim is a suppressor of Myc-induced mouse B cell leukemia

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7 January 2021

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

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7 January 2021

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

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7 January 2021

Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors

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7 January 2021

MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

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https://api.crossref.org/works/10.1038%2FLEU.2011.305

7 January 2021

MicroRNA 92b controls the G1/S checkpoint gene p57 in human embryonic stem cells.

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7 January 2021

The myc-miR-17~92 axis blunts TGF{beta} signaling and production of multiple TGF{beta}-dependent antiangiogenic factors

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7 January 2021

Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells

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7 January 2021

An E2F/miR-20a autoregulatory feedback loop.

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7 January 2021

The miR-17-92 microRNA cluster is regulated by multiple mechanisms in B-cell malignancies

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7 January 2021

Subcellular localization of glycogen synthase kinase 3beta controls embryonic stem cell self-renewal

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7 January 2021

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

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7 January 2021

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms.

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7 January 2021

Antagomir-17-5p abolishes the growth of therapy-resistant neuroblastoma through p21 and BIM

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7 January 2021

Identifiers

DOI

10.1038/LEU.2011.305

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12 September 2017

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