Assessment of the transforming potential of novel anaplastic lymphoma kinase point mutants (Q39442482)

12 September 2017

title

Assessment of the transforming potential of novel anaplastic lymphoma kinase point mutants (English)

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12 September 2017

4

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12 September 2017

Fiona K E McDuff

1

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12 September 2017

Su-Vern Lim

series ordinal

2

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12 September 2017

Melis Dalbay

series ordinal

3

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12 September 2017

publication date

15 November 2011

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12 September 2017

published in

Molecular Carcinogenesis

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12 September 2017

volume

52

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12 September 2017

issue

1

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12 September 2017

page(s)

79-83

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Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system

12 September 2017

cites work

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Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

21 January 2018

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Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types

21 January 2018

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Jeb signals through the Alk receptor tyrosine kinase to drive visceral muscle fusion.

21 January 2018

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Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers.

21 January 2018

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Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications

21 January 2018

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Translocations involving anaplastic lymphoma kinase (ALK).

21 January 2018

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Oncogenic mutations of ALK kinase in neuroblastoma

21 January 2018

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Activating mutations in ALK provide a therapeutic target in neuroblastoma

21 January 2018

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Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

21 January 2018

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Identification of ALK as a major familial neuroblastoma predisposition gene

21 January 2018

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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

21 January 2018

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Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)

21 January 2018

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What have we learnt from mouse models of NPM-ALK-induced lymphomagenesis?

21 January 2018

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Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis

21 January 2018

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Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain

21 January 2018

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Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.

21 January 2018

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Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors

21 January 2018

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Aberrant anaplastic lymphoma kinase activity induces a p53 and Rb-dependent senescence-like arrest in the absence of detectable p53 stabilization

21 January 2018

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NPM-ALK inhibits the p53 tumor suppressor pathway in an MDM2 and JNK-dependent manner.

21 January 2018

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Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MC.21836

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release_exo3wc32qzbodljj6i2sdjlfdm

12 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/exo3wc32qzbodljj6i2sdjlfdm

mapped directly with Wikidata item

24 November 2022

based on heuristic

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