Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity (Q39445705)

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English	Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 September 2017

Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

author name string

Tsubari M

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Taipale J

2

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Europe PubMed Central

PMC publication ID

12 September 2017

Tiihonen E

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Keski-Oja J

4

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Europe PubMed Central

PMC publication ID

12 September 2017

Laiho M

5

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Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

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publication date

1 May 1999

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Europe PubMed Central

PMC publication ID

12 September 2017

Molecular and Cellular Biology

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Europe PubMed Central

PMC publication ID

12 September 2017

19

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

3654-3663

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

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12 September 2017

Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation

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12 September 2017

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Cancer cell cycles

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12 September 2017

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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12 September 2017

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

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12 September 2017

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

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The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

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12 September 2017

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

G1 phase progression: cycling on cue

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12 September 2017

Principles of CDK regulation

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12 September 2017

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

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12 September 2017

Inhibitors of mammalian G1 cyclin-dependent kinases

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12 September 2017

The retinoblastoma protein and cell cycle control

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1 reference

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12 September 2017

Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Role of phosphorylation in p34cdc2 activation: identification of an activating kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Phosphorylation of the retinoblastoma protein by cdk2

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

12 September 2017

Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

14 September 2017

Cyclins and cyclin-dependent kinases: theme and variations

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

14 September 2017

Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs).

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14 September 2017

TGFbeta signaling: receptors, transducers, and Mad proteins.

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25 September 2017

Molecular aspects of mesenchymal-epithelial interactions

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25 September 2017

p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast

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25 September 2017

Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFbeta-treated cells

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25 September 2017

Hepatocyte growth factor releases epithelial and endothelial cells from growth arrest induced by transforming growth factor-beta1.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84171

25 September 2017

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

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25 September 2017

Cell cycle dependent effects of u.v.-radiation on p53 expression and retinoblastoma protein phosphorylation.

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25 September 2017

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

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25 September 2017

Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein

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17 June 2018

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

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17 June 2018

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

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17 June 2018

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

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17 June 2018

A new method for high yield purification of type beta transforming growth factor from human platelets.

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17 June 2018

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

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17 June 2018

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

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17 June 2018

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

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Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion.

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Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.

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Association of human cyclin E with a periodic G1-S phase protein kinase

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Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

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Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

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Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

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Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

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12 December 2020

based on heuristic

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Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex

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12 December 2020

based on heuristic

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Identifiers

10.1128/MCB.19.5.3654

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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