DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and β-catenin nuclear translocation (Q39449462)

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English	DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and β-catenin nuclear translocation	scientific article

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scholarly article

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Europe PubMed Central

12 September 2017

DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and β-catenin nuclear translocation (English)

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Europe PubMed Central

12 September 2017

apoptotic process

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author name string

Simona Serini

1

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Europe PubMed Central

12 September 2017

Elena Fasano

2

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Europe PubMed Central

12 September 2017

Elisabetta Piccioni

3

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Europe PubMed Central

12 September 2017

Giovanni Monego

4

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Europe PubMed Central

12 September 2017

Achille R M Cittadini

5

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Europe PubMed Central

12 September 2017

Leonardo Celleno

6

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Europe PubMed Central

12 September 2017

Franco O Ranelletti

7

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Europe PubMed Central

12 September 2017

Gabriella Calviello

8

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Europe PubMed Central

12 September 2017

language of work or name

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publication date

31 October 2011

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Europe PubMed Central

12 September 2017

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Europe PubMed Central

12 September 2017

33

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Europe PubMed Central

12 September 2017

1

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12 September 2017

164-173

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12 September 2017

Cancer statistics, 2009

1 reference

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Are some melanomas caused by artificial light?

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Conditional ablation of Ikkb inhibits melanoma tumor development in mice

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Suppression of the proinflammatory response of metastatic melanoma cells increases TRAIL-induced apoptosis

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Progress in COX-2 inhibitors: a journey so far.

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Cyclooxygenases, prostanoids, and tumor progression

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Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis.

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Cyclo-oxygenase-2 and its inhibition in cancer: is there a role?

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Cyclooxygenase-2 (COX-2): first immunohistochemical marker distinguishing early cutaneous melanomas from benign melanocytic skin tumours.

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Impressive regression of visceral and cerebral melanoma metastases under combination treatment including dacarbacine, radiotherapy and celecoxib

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Cyclooxygenase inhibitors: scope of their use and development in cancer chemotherapy

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Similar antineoplastic effects of nimesulide, a selective COX-2 inhibitor, and prostaglandin E1 on B16-F10 murine melanoma cells.

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Expression of Ca(2+)-independent and Ca(2+)-dependent phospholipases A(2) and cyclooxygenases in human melanocytes and malignant melanoma cell lines.

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A phase 2 pilot trial of low-dose, continuous infusion, or "metronomic" paclitaxel and oral celecoxib in patients with metastatic melanoma

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Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk

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Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2.

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Prostate tumor growth can be modulated by dietarily targeting the 15-lipoxygenase-1 and cyclooxygenase-2 enzymes.

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n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway

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Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2.

1 reference

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21 January 2018

n-3 polyunsaturated fatty acids and the prevention of colorectal cancer: molecular mechanisms involved.

1 reference

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21 January 2018

Dietary n-3 PUFA vascular targeting and the prevention of tumor growth and age-related macular degeneration.

1 reference

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21 January 2018

Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer.

1 reference

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21 January 2018

Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma

1 reference

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21 January 2018

UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes

1 reference

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21 January 2018

Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells

1 reference

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21 January 2018

Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression

1 reference

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21 January 2018

Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR.

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21 January 2018

Posttranscriptional orchestration of an anti-apoptotic program by HuR.

1 reference

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21 January 2018

Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3'-UTR.

1 reference

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21 January 2018

Immunoprecipitation of mRNA-protein complexes.

1 reference

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21 January 2018

Cyclooxygenases: structural and functional insights

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21 January 2018

alphaV integrin promotes in vitro and in vivo survival of cells in metastatic melanoma

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21 January 2018

Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2.

1 reference

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21 January 2018

A new cyclooxygenase-2 inhibitor, (1E,4E)-1,5-bis(2-bromophenyl)penta-1,4-dien-3-one (GL63) suppresses cyclooxygenase-2 gene expression in human lung epithelial cancer cells: coupled mRNA stabilization and posttranscriptional inhibition.

1 reference

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21 January 2018

Expression of HuR is associated with increased cyclooxygenase-2 expression in uterine cervical carcinoma.

1 reference

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21 January 2018

Cyclooxygenase-2 expression is critical for chronic UV-induced murine skin carcinogenesis

1 reference

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Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression

1 reference

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Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

1 reference

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Docosahexaenoic acid induces adipose differentiation-related protein through activation of retinoid x receptor in human choriocarcinoma BeWo cells

1 reference

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Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR

1 reference

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21 January 2018

Identifiers

10.1093/CARCIN/BGR240

1 reference

Europe PubMed Central

12 September 2017

1 reference

Europe PubMed Central

12 September 2017

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