Costimulation by chimeric antigen receptors revisited the T cell antitumor response benefits from combined CD28-OX40 signalling (Q39452134)

12 September 2017

title

Costimulation by chimeric antigen receptors revisited the T cell antitumor response benefits from combined CD28-OX40 signalling (English)

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12 September 2017

Andreas A Hombach

1

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12 September 2017

Hinrich Abken

series ordinal

2

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12 September 2017

language of work or name

English

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publication date

29 March 2011

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International Journal of Cancer

12 September 2017

published in

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12 September 2017

volume

129

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12 September 2017

issue

12

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12 September 2017

page(s)

2935-2944

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Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors

12 September 2017

cites work

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Adoptive immunotherapy for cancer: the next generation of gene-engineered immune cells.

21 January 2018

1 reference

The promise and potential pitfalls of chimeric antigen receptors

21 January 2018

1 reference

Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

21 January 2018

1 reference

A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

21 January 2018

1 reference

Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain

21 January 2018

1 reference

Building better chimeric antigen receptors for adoptive T cell therapy

21 January 2018

1 reference

Targeting tumours with genetically enhanced T lymphocytes

21 January 2018

1 reference

Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRζ /CD28 receptor

21 January 2018

1 reference

TNF/TNFR family members in costimulation of T cell responses

21 January 2018

1 reference

A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells

21 January 2018

1 reference

Tuning tumor-specific T-cell activation: a matter of costimulation?

21 January 2018

1 reference

Treatment of chronic lymphocytic leukemia with genetically targeted autologous T cells: case report of an unforeseen adverse event in a phase I clinical trial

21 January 2018

1 reference

Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

21 January 2018

1 reference

21 January 2018

1 reference

A retroviral vector system 'STITCH' in combination with an optimized single chain antibody chimeric receptor gene structure allows efficient gene transduction and expression in human T lymphocytes

21 January 2018

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A recombinant anti-carcinoembryonic antigen immunoreceptor with combined CD3zeta-CD28 signalling targets T cells from colorectal cancer patients against their tumour cells

21 January 2018

1 reference

CD4+ T cells engrafted with a recombinant immunoreceptor efficiently lyse target cells in a MHC antigen- and Fas-independent fashion.

21 January 2018

1 reference

Preferential localization of effector memory cells in nonlymphoid tissue

21 January 2018

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Development, trafficking, and function of memory T-cell subsets

21 January 2018

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Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains.

21 January 2018

1 reference

Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses.

21 January 2018

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Integrating costimulatory agonists to optimize immune-based cancer therapies

21 January 2018

1 reference

4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity

21 January 2018

1 reference

Treatment of lymphoma with adoptively transferred T cells.

21 January 2018

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

21 January 2018

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T cell activation by antibody-like immunoreceptors: increase in affinity of the single-chain fragment domain above threshold does not increase T cell activation against antigen-positive target cells but decreases selectivity.

21 January 2018

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CD28 cosignalling does not affect the activation threshold in a chimeric antigen receptor-redirected T-cell attack

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.25960

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12 September 2017

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