Role of STAT3/5 and Bcl-2/xL in 2-methoxyestradiol-induced endoreduplication of nasopharyngeal carcinoma cells (Q39456688)

12 September 2017

title

Role of STAT3/5 and Bcl-2/xL in 2-methoxyestradiol-induced endoreduplication of nasopharyngeal carcinoma cells (English)

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12 September 2017

C M Ting

1

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12 September 2017

Chris K C Wong

2

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12 September 2017

R N S Wong

3

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12 September 2017

K W Lo

4

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12 September 2017

Anne W M Lee

5

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12 September 2017

George S W Tsao

6

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12 September 2017

Maria L Lung

7

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12 September 2017

N K Mak

8

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12 September 2017

publication date

17 October 2011

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12 September 2017

published in

Molecular Carcinogenesis

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12 September 2017

volume

51

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12 September 2017

issue

12

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12 September 2017

page(s)

963-972

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12 September 2017

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Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy.

21 January 2018

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Synergistic antimicrotubule therapy for prostate cancer

21 January 2018

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Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II.

21 January 2018

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Human B lymphocytes and non-Hodgkin's lymphoma cells become polyploid in response to the protein kinase inhibitor SU6656.

21 January 2018

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The nature of DNA plays a role in chromosome segregation: endoreduplication in halogen-substituted chromosomes.

21 January 2018

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Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

21 January 2018

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Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization

21 January 2018

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Phase II study of docetaxel, cisplatin, and 5-FU induction chemotherapy followed by chemoradiotherapy in locoregionally advanced nasopharyngeal cancer

21 January 2018

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The hematopoietic-specific beta1-tubulin is naturally resistant to 2-methoxyestradiol and protects patients from drug-induced myelosuppression

21 January 2018

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2-Methoxyestradiol induces endoreduplication through the induction of mitochondrial oxidative stress and the activation of MAPK signaling pathways

21 January 2018

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Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of the nasopharynx.

21 January 2018

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Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus

21 January 2018

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Mechanisms of 2-methoxyestradiol-induced apoptosis and G2/M cell-cycle arrest of nasopharyngeal carcinoma cells.

21 January 2018

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Tetraploidy, aneuploidy and cancer

21 January 2018

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Endoreplication cell cycles: more for less

21 January 2018

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Endoreduplication induced in cultured Chinese hamster cells by different anti-topoisomerase II chemicals. Evidence for the essential contribution of the enzyme to chromosome segregation.

21 January 2018

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MYC prevents apoptosis and enhances endoreduplication induced by paclitaxel

21 January 2018

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Concurrent chemoradiotherapy in the management of advanced nasopharyngeal carcinoma: current status

21 January 2018

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2-Methoxyestradiol--biology and mechanism of action

21 January 2018

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Structure activity analysis of 2-methoxyestradiol analogues reveals targeting of microtubules as the major mechanism of antiproliferative and proapoptotic activity

21 January 2018

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Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?

21 January 2018

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Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis

21 January 2018

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Reactive nitrogen species-dependent DNA damage in EBV-associated nasopharyngeal carcinoma: the relation to STAT3 activation and EGFR expression

21 January 2018

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STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro.

21 January 2018

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STAT3 activation induced by Epstein-Barr virus latent membrane protein1 causes vascular endothelial growth factor expression and cellular invasiveness via JAK3 And ERK signaling.

21 January 2018

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Defining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: implications for future therapeutic approaches

21 January 2018

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Factors contributing to the efficacy of concurrent–adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma: Combined analyses of NPC-9901 and NPC-9902 Trials

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MC.20867

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12 September 2017

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