Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells (Q39468269)

12 September 2017

Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells (English)

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12 September 2017

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R Schwarzer

1

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PubMed ID

21946908

12 September 2017

B Dörken

series ordinal

2

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PubMed ID

21946908

12 September 2017

F Jundt

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3

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12 September 2017

27 September 2011

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12 September 2017

26

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806-813

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https://scigraph.springernature.com/pub.10.1038/leu.2011.265

12 September 2017

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cites work

The canonical Notch signaling pathway: unfolding the activation mechanism

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

High-level expression of Mastermind-like 2 contributes to aberrant activation of the NOTCH signaling pathway in human lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

The biology of Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

TRAF1 is involved in the classical NF-kappaB activation and CD30-induced alternative activity in Hodgkin's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

IkappaBalpha degradation and nuclear factor-kappaB DNA binding are insufficient for interleukin-1beta and tumor necrosis factor-alpha-induced kappaB-dependent transcription. Requirement for an additional activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

IkappaB kinase complexes: gateways to NF-kappaB activation and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Expression of CCR5 receptors on Reed-Sternberg cells and Hodgkin lymphoma cell lines: involvement of CCL5/Rantes in tumor cell growth and microenvironmental interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Expression of functional interleukin-3 receptors on Hodgkin and Reed-Sternberg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Notch inhibition blocks multiple myeloma cell-induced osteoclast activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Cancer stem cells: problems for therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

Notch signaling in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

7 January 2021

Off the beaten pathway: the complex cross talk between Notch and NF-kappaB

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

7 January 2021

Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

7 January 2021

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.265

7 January 2021

Identifiers

DOI

10.1038/LEU.2011.265

1 reference

12 September 2017

1 reference

PubMed ID

21946908