A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53 (Q39489233)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

title

A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

author name string

K L Sugars

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

V Budhram-Mahadeo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

D S Latchman

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

language of work or name

English

0 references

publication date

1 November 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

page(s)

4530-4540

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

The BRN-3A transcription factor protects sensory but not sympathetic neurons from programmed cell death/apoptosis

3 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

p53 suppresses the activation of the Bcl-2 promoter by the Brn-3a POU family transcription factor

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bbcl-2 gene expression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Bcl-2 transcription from the proximal P2 promoter is activated in neuronal cells by the Brn-3a POU family transcription factor

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Alternative splicing of the Brn-3a and Brn-3b transcription factor RNAs is regulated in neuronal cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Activation of the alpha-internexin promoter by the Brn-3a transcription factor is dependent on the N-terminal region of the protein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Expression of a large family of POU-domain regulatory genes in mammalian brain development

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Regulation of NGFI-A (Egr-1) gene expression by the POU domain transcription factor Brn-3a

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

POU domain transcription factors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Transactivational and DNA binding abilities of endogenous p53 in p53 mutant cell lines

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Regulation of neurite outgrowth and SNAP-25 gene expression by the Brn-3a transcription factor

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Genomic organization, promoter region analysis, and chromosome localization of the mouse bcl-x gene.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Novel cell lines display properties of nociceptive sensory neurons.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

POU domain family values: flexibility, partnerships, and developmental codes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=92563

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11713302

12 December 2020

inferred from PubMed ID database lookup

Identification of a novel human BCL-X promoter and exon

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11713302

12 December 2020

inferred from PubMed ID database lookup

Brn-3a activates the expression of Bcl-x(L) and promotes neuronal survival in vivo as well as in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11713302

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/29.22.4530

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

release_n4bomckclvazzer25764yb3qda

3 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/n4bomckclvazzer25764yb3qda

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11713302%20AND%20SRC:MED&resulttype=core&format=json