Lymphocyte α-kinase is a gout-susceptible gene involved in monosodium urate monohydrate-induced inflammatory responses. (Q39493628)

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9 February 2020

title

Lymphocyte α-kinase is a gout-susceptible gene involved in monosodium urate monohydrate-induced inflammatory responses (English)

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9 February 2020

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9 February 2020

author name string

Shu-Jung Wang

1

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9 February 2020

Albert Min-Shan Ko

3

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9 February 2020

Shang-Lun Chiang

4

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9 February 2020

Shean-Jaw Chiou

5

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9 February 2020

Su-Shin Lee

6

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9 February 2020

Yi-Shan Tsai

7

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Chi-Pin Lee

8

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9 February 2020

Ying-Chin Ko

9

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publication date

7 August 2011

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Journal of Molecular Medicine

9 February 2020

published in

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volume

89

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issue

12

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page(s)

1241-1251

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https://scigraph.springernature.com/pub.10.1007/s00109-011-0796-5

9 February 2020

exact match

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cites work

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Genomewide scan for gout in taiwanese aborigines reveals linkage to chromosome 4q25.

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Alpha-kinases: a new class of protein kinases with a novel catalytic domain

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Alpha-kinase 1, a new component in apical protein transport

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Gout: on the brink of novel therapeutic options for an ancient disease

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Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution

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Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expr

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Signaling events involved in macrophage chemokine expression in response to monosodium urate crystals.

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Preliminary criteria for the classification of the acute arthritis of primary gout

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Purine-rich foods, dairy and protein intake, and the risk of gout in men.

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Upregulation of SOX9 in lung adenocarcinoma and its involvement in the regulation of cell growth and tumorigenicity

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Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology

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Monosodium urate monohydrate crystal-induced inflammation in vivo: quantitative histomorphometric analysis of cellular events.

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Gout-associated uric acid crystals activate the NALP3 inflammasome

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Monosodium urate and calcium pyrophosphate dihydrate (CPPD) crystals, inflammation, and cellular signaling.

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Noninflammatory phagocytosis of monosodium urate monohydrate crystals by mouse macrophages. Implications for the control of joint inflammation in gout

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Safe disposal of inflammatory monosodium urate monohydrate crystals by differentiated macrophages.

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Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.

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The role of interleukin-1 and the inflammasome in gout: implications for therapy

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Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout

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Phosphorylation of annexin I by TRPM7 channel-kinase

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Elongation factor-2 kinase and its newly discovered relatives

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Motor coordination deficits in Alpk1 mutant mice with the inserted piggyBac transposon

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Myosin-1a powers the sliding of apical membrane along microvillar actin bundles.

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PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes

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The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus

21 January 2018

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Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.

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Src family protein tyrosine kinase signaling mediates monosodium urate crystal-induced IL-8 expression by monocytic THP-1 cells

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12 December 2020

Monosodium urate monohydrate crystal-recruited noninflammatory monocytes differentiate into M1-like proinflammatory macrophages in a peritoneal murine model of gout

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Novel type of signaling molecules: protein kinases covalently linked to ion channels

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Molecular identification of a renal urate anion exchanger that regulates blood urate levels

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Monosodium urate crystals stimulate phospholipase A2 enzyme activities and the synthesis of a phospholipase A2-activating protein

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Activation of Lyn is a common element of the stimulation of human neutrophils by soluble and particulate agonists

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12 December 2020

10.1007/S00109-011-0796-5

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21822924%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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