Gene targeting in Penicillium chrysogenum: disruption of the lys2 gene leads to penicillin overproduction. (Q39494258)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9973344%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

title

Gene targeting in Penicillium chrysogenum: disruption of the lys2 gene leads to penicillin overproduction (English)

1 reference

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11 December 2019

1 reference

Penicillium chrysogenum

object named as

Penicillium chrysogenum

1 reference

1

1 reference

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11 December 2019

author name string

S Gutiérrez

2

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11 December 2019

O Bañuelos

3

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11 December 2019

M J Hijarrubia

4

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11 December 2019

J F Martín

5

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11 December 2019

language of work or name

English

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publication date

1 February 1999

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11 December 2019

published in

Journal of Bacteriology

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11 December 2019

volume

181

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11 December 2019

issue

4

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11 December 2019

page(s)

1181-1188

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Transcription of the pcbAB, pcbC and penDE genes of Penicillium chrysogenum AS-P-78 is repressed by glucose and the repression is not reversed by alkaline pHs.

11 December 2019

cites work

1 reference

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Characterization of the lys2 gene of Penicillium chrysogenum encoding alpha-aminoadipic acid reductase.

12 September 2017

1 reference

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Molecular analysis of the LYS2 gene of Candida albicans: homology to peptide antibiotic synthetases and the regulation of the alpha-aminoadipate reductase

12 September 2017

1 reference

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Gene targeting is locus dependent in the filamentous fungus Aspergillus nidulans

12 September 2017

1 reference

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Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis

12 September 2017

1 reference

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Molecular characterization of three loss-of-function mutations in the isopenicillin N-acyltransferase gene (penDE) of Penicillium chrysogenum

12 September 2017

1 reference

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Plasmids containing mouse rDNA do not recombine with cellular ribosomal genes when introduced into cultured mouse cells

12 September 2017

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[12] One-step gene disruption in yeast

12 September 2017

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Yeast transformation: a model system for the study of recombination

12 September 2017

1 reference

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Lysine biosynthesis in Saccharomyces. Conversion of -aminoadipate into -aminoadipic -semialdehyde

12 September 2017

1 reference

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Homologous recombination in Escherichia coli: dependence on substrate length and homology

12 September 2017

1 reference

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Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae

12 September 2017

1 reference

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Replacement of chromosome segments with altered DNA sequences constructed in vitro

12 September 2017

1 reference

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Uptake and metabolism of ?-aminoadipic acid by Penicillium chrysogenum wis 54-1255

12 September 2017

1 reference

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Lysine Regulation of Penicillin Biosynthesis in Low-producing and Industrial Strains of Penicillium chrysogenum

12 September 2017

1 reference

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Inhibition and repression of homocitrate synthase by lysine in Penicillium chrysogenum

14 September 2017

1 reference

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Nucleotide sequence of the Penicillium chrysogenum pyrG (orotidine-5'-phosphate decarboxylase) gene

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=93495

The length of homology required for gene targeting in embryonic stem cells

14 September 2017

1 reference

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Targeted integration into the Acremonium chrysogenum genome: disruption of the pcbC gene.

14 September 2017

1 reference

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Gene inactivation in the plant pathogen Glomerella cingulata: three strategies for the disruption of the pectin lyase gene pnlA.

15 June 2018

1 reference

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Regulation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and isopenicillin N biosynthesis in Penicillium chrysogenum by the alpha-aminoadipate pool size

15 June 2018

1 reference

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Homologous recombination between plasmid and chromosomal DNA in Bacillus subtilis requires approximately 70 bp of homology

15 June 2018

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Regulation of acid phosphatases in an Aspergillus niger pacC disruption strain.

15 June 2018

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Relationship of vector insert size to homologous integration during transformation of Neurospora crassa with the cloned am (GDH) gene

21 August 2018

1 reference

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Studies in lysine biosynthesis. IV. Mechanism of activation and reduction of alpha-aminoadipic acid

21 August 2018

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12 December 2020

Expression of the penDE gene of Penicillium chrysogenum encoding isopenicillin N acyltransferase in Cephalosporium acremonium: production of benzylpenicillin by the transformants

1 reference

12 December 2020

Gene disruption of the pcbAB gene encoding ACV synthetase in Cephalosporium acremonium

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12 December 2020

Transformation of Neurospora crassa with circular and linear DNA and analysis of the fate of the transforming DNA

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12 December 2020

alpha-Aminoadipate pool concentration and penicillin biosynthesis in strains of Penicillium chrysogenum

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12 December 2020

Transforming DNA integrates into the host chromosome

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12 December 2020

Efficient gene targeting in the filamentous fungusAlternaria alternata

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12 December 2020

Mutants blocked in penicillin biosynthesis show a deletion of the entire penicillin gene cluster at a specific site within a conserved hexanucleotide sequence

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12 December 2020

One-step gene disruption in yeast

1 reference

12 December 2020