GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells (Q39498508)

12 September 2017

GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells (English)

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12 September 2017

Delphine Javelaud

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Corine Bertolotto

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Corine Bertolotto

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Veronique Delmas

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Véronique Delmas

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Robert Ballotti

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Robert Ballotti

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author name string

Vasileia-Ismini Alexaki

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12 September 2017

Marie-Jeanne Pierrat

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12 September 2017

Keith S Hoek

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12 September 2017

Sylviane Dennler

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12 September 2017

Leon Van Kempen

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12 September 2017

Simon Saule

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12 September 2017

Alain Mauviel

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12 September 2017

18 August 2011

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Pigment Cell & Melanoma Research

12 September 2017

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12 September 2017

24

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12 September 2017

5

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12 September 2017

932-943

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JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.

12 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

GLI2-mediated melanoma invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Smad7 restricts melanoma invasion by restoring N-cadherin expression and establishing heterotypic cell-cell interactions in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Microphthalmia-associated transcription factor (MITF) is required but is not sufficient to induce the expression of melanogenic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Cancer stem cells versus phenotype-switching in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Novel MITF targets identified using a two-step DNA microarray strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Transforming growth factor-beta in cutaneous melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Confirmation of a BRAF mutation-associated gene expression signature in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

GLI transcription factors: mediators of oncogenic Hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

MITF: master regulator of melanocyte development and melanoma oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Developmental roles and clinical significance of hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Involvement of cadherins 7 and 20 in mouse embryogenesis and melanocyte transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Gli and hedgehog in cancer: tumours, embryos and stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Melanocytes and the microphthalmia transcription factor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Enhanced melanogenesis induced by tyrosinase gene-transfer increases boron-uptake and killing effect of boron neutron capture therapy for amelanotic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Transcriptional repression of the microphthalmia gene in melanoma cells correlates with the unresponsiveness of target genes to ectopic microphthalmia-associated transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00893.X

10.1111/J.1755-148X.2011.00893.X

21 January 2018

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12 September 2017

1 reference