Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase. (Q39499581)

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8 February 2020

title

Human cutaneous melanomas lacking MITF and melanocyte differentiation antigens express a functional Axl receptor kinase (English)

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8 February 2020

12

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Marialuisa Sensi

1

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8 February 2020

Giancarlo Castellano

3

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8 February 2020

Antonella Tomassetti

10

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author name string

Mara Catani

2

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8 February 2020

Gabriella Nicolini

4

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8 February 2020

Federica Alciato

5

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Gabrina Tragni

6

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8 February 2020

Giuseppina De Santis

7

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8 February 2020

Ilaria Bersani

8

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8 February 2020

Giancarlo Avanzi

9

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Silvana Canevari

11

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8 February 2020

language of work or name

English

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publication date

28 July 2011

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Journal of Investigative Dermatology

8 February 2020

published in

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volume

131

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issue

12

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page(s)

2448-2457

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https://scigraph.springernature.com/pub.10.1038/jid.2011.218

8 February 2020

exact match

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cites work

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E-cadherin directly contributes to PI3K/AKT activation by engaging the PI3K-p85 regulatory subunit to adherens junctions of ovarian carcinoma cells

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7 January 2021

Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival

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Bioinformatic identification of potential autocrine signaling loops in cancers from gene expression profiles

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Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

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Novel MITF targets identified using a two-step DNA microarray strategy

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R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer

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7 January 2021

Multiple roles for the receptor tyrosine kinase axl in tumor formation

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A gene expression signature of invasive potential in metastatic melanoma cells

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

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7 January 2021

Frequencies of BRAF and NRAS mutations are different in histological types and sites of origin of cutaneous melanoma: a meta-analysis

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7 January 2021

Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

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7 January 2021

Transcriptional regulation in melanoma

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7 January 2021

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

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7 January 2021

Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma

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7 January 2021

Microarray expression profiling in melanoma reveals a BRAF mutation signature.

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Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

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7 January 2021

Protein kinases in normal and transformed melanocytes

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7 January 2021

Analyzing real-time PCR data by the comparative C(T) method

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7 January 2021

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

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7 January 2021

Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzyme peroxiredoxin 5.

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7 January 2021

Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-kappaB and Brg-1.

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7 January 2021

Expression of the receptor tyrosine kinase Axl promotes ocular melanoma cell survival

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7 January 2021

Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6

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7 January 2021

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

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7 January 2021

An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies

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7 January 2021

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7 January 2021

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

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7 January 2021