DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway (Q39500011)

12 September 2017

DA6034 promotes gastric epithelial cell migration and wound-healing through the mTOR pathway (English)

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12 September 2017

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Young Woo Kim

1

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12 September 2017

Woo Hyung Lee

2

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12 September 2017

Seul Min Choi

3

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12 September 2017

Yoon Young Seo

4

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12 September 2017

Byoung Ok Ahn

5

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12 September 2017

Soon Hoe Kim

6

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12 September 2017

Sang Geon Kim

7

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12 September 2017

1 February 2012

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Journal of Gastroenterology and Hepatology

12 September 2017

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12 September 2017

27

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12 September 2017

2

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12 September 2017

397-405

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Mechanisms for rapid re-epithelialization of the gastric mucosal surface

12 September 2017

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Wound healing--aiming for perfect skin regeneration

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Mammalian TOR: a homeostatic ATP sensor

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Accelerated wound healing by mTOR activation in genetically defined mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

The therapeutic effect of DA-6034 on ocular inflammation via suppression of MMP-9 and inflammatory cytokines and activation of the MAPK signaling pathway in an experimental dry eye model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Gastroprotective effects of DA-6034, a new flavonoid derivative, in various gastric mucosal damage models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

DA-6034, a derivative of flavonoid, prevents and ameliorates dextran sulfate sodium-induced colitis and inhibits colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Inhibition of LXRα-dependent steatosis and oxidative injury by liquiritigenin, a licorice flavonoid, as mediated with Nrf2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

G alpha 12/13 basally regulates p53 through Mdm4 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Differential growth factor induction and modulation of human gastric epithelial regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Cellular and molecular mechanisms of gastrointestinal ulcer healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Lansoprazole promotes gastric mucosal cell proliferation and migration by activating p44/p42 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Dexamethasone inhibits tumor necrosis factor-alpha-stimulated gastric epithelial cell migration

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Ecabet sodium prevents the delay of wound repair in intestinal epithelial cells induced by hydrogen peroxide

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Omeprazole promotes gastric epithelial cell migration

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

mTORC2 regulates PGE2-mediated endothelial cell survival and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Involvement of phosphatidylinositol 3-kinase in cAMP- and cGMP-induced duodenal epithelial CFTR activation in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Drug discovery approaches targeting the PI3K/Akt pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

PI3K/Akt and apoptosis: size matters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: attractive targets for molecular-oriented therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

Pharmacokinetics of DA-6034, an agent for inflammatory bowel disease, in rats and dogs: Contribution of intestinal first-pass effect to low bioavailability in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1746.2011.06873.X

10.1111/J.1440-1746.2011.06873.X

21 January 2018

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DOI

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12 September 2017

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