MDCK cell line with inducible allele B NS1 expression propagates delNS1 influenza virus to high titres (Q39501163)

12 September 2017

MDCK cell line with inducible allele B NS1 expression propagates delNS1 influenza virus to high titres (English)

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12 September 2017

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R van Wielink

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12 September 2017

M M Harmsen

2

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12 September 2017

D E Martens

3

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12 September 2017

B P H Peeters

4

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12 September 2017

R H Wijffels

5

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12 September 2017

R J M Moormann

6

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12 September 2017

language of work or name

English

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publication date

23 July 2011

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12 September 2017

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12 September 2017

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40

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12 September 2017

6976-6985

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Attenuated influenza virus vaccines with modified NS1 proteins

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Development of a live-attenuated influenza B DeltaNS1 intranasal vaccine candidate.

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The multifunctional NS1 protein of influenza A viruses

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High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state.

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Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamics

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Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

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Variation in the ability of human influenza A viruses to induce and inhibit the IFN-beta pathway.

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Multiple anti-interferon actions of the influenza A virus NS1 protein

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NS reassortment of an H7-type highly pathogenic avian influenza virus affects its propagation by altering the regulation of viral RNA production and antiviral host response

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NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome

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Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses

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Properties of H7N7 influenza A virus strain SC35M lacking interferon antagonist NS1 in mice and chickens

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Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

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Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach

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Adaptation of a Madin-Darby canine kidney cell line to suspension growth in serum-free media and comparison of its ability to produce avian influenza virus to Vero and BHK21 cell lines

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Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs

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Highly pathogenic avian influenza A virus H5N1 NS1 protein induces caspase-dependent apoptosis in human alveolar basal epithelial cells

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Avian influenza virus A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells.

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H5N1 avian influenza virus induces apoptotic cell death in mammalian airway epithelial cells.

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Influenza virus ns1 protein induces apoptosis in cultured cells

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Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells

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Eight-plasmid system for rapid generation of influenza virus vaccines

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A DNA transfection system for generation of influenza A virus from eight plasmids

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Nucleocytoplasmic transport: the influenza virus NS1 protein regulates the transport of spliced NS2 mRNA and its precursor NS1 mRNA.

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Tissue tropism in the chicken embryo of non-virulent and virulent Newcastle diseases strains that express green fluorescence protein

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Autocrine amplification of type I interferon gene expression mediated by interferon stimulated gene factor 3 (ISGF3).

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Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

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Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18

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Differential regulation of antiviral and proinflammatory cytokines and suppression of Fas-mediated apoptosis by NS1 of H9N2 avian influenza virus in chicken macrophages

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NS1 protein of influenza A virus down-regulates apoptosis

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Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K).

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The non-structural (NS1) protein of influenza A virus associates with p53 and inhibits p53-mediated transcriptional activity and apoptosis.

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Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling

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Strong interferon-inducing capacity of a highly virulent variant of influenza A virus strain PR8 with deletions in the NS1 gene

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Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

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Differences in the ability to suppress interferon β production between allele A and allele B NS1 proteins from H10 influenza A viruses.

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Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 protein

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10.1016/J.VACCINE.2011.07.037

7 January 2021

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DOI

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12 September 2017

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