Nandrolone and stanozolol induce Leydig cell tumor proliferation through an estrogen-dependent mechanism involving IGF-I system. (Q39504547)

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7 February 2020

title

Nandrolone and stanozolol induce Leydig cell tumor proliferation through an estrogen-dependent mechanism involving IGF-I system (English)

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ChEBI release 2020-05-28

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2

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Marilena Lanzino

5

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Stefania Catalano

6

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Vincenzo Pezzi

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author name string

Adele Chimento

1

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Fabiana Zolea

3

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Arianna De Luca

4

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Sebastiano Andò

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publication date

1 May 2012

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Journal of Cellular Physiology

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published in

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volume

227

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issue

5

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page(s)

2079-2088

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Effects of an Igf1 gene null mutation on mouse reproduction

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cites work

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Older men are as responsive as young men to the anabolic effects of graded doses of testosterone on the skeletal muscle

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Isolation of rat testis cDNAs encoding an insulin-like growth factor I precursor

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Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells

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Overexpression of aromatase leads to development of testicular leydig cell tumors : an in vivo model for hormone-mediated TesticularCancer

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DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells

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Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.

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Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway

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Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors

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Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation.

21 January 2018

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Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells

21 January 2018

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Hepatocellular adenomas associated with anabolic androgenic steroid abuse in bodybuilders: a report of two cases and a review of the literature

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Role of receptor complexes in the extranuclear actions of estrogen receptor alpha in breast cancer

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Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability

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Effects of insulin-like growth factor I on steroidogenic enzyme expression levels in mouse leydig cells

21 January 2018

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Identifiers

DOI

10.1002/JCP.22936

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7 February 2020

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