Homology Model and Docking-Based Virtual Screening for Ligands of the σ1 Receptor. (Q39508226)

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20 March 2020

title

Homology Model and Docking-Based Virtual Screening for Ligands of the σ1 Receptor (English)

1 reference

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20 March 2020

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6

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20 March 2020

Sabrina Pricl

series ordinal

8

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20 March 2020

5

Paola Posocco

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20 March 2020

1

Erik Laurini

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20 March 2020

2

Valentina Dal Col

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20 March 2020

3

Maria Grazia Mamolo

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20 March 2020

4

Daniele Zampieri

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7

Luciano Vio

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publication date

27 August 2011

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ACS Medicinal Chemistry Letters

20 March 2020

published in

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volume

2

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issue

11

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20 March 2020

page(s)

834-839

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Sigma receptors: potential targets for a new class of antidepressant drug

20 March 2020

cites work

1 reference

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The pharmacology of sigma-1 receptors

12 September 2017

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Pharmacology and therapeutic potential of sigma(1) receptor ligands

12 September 2017

1 reference

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Substituted benzo[d]oxazol-2(3H)-one derivatives with preference for the sigma1 binding site

12 September 2017

1 reference

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Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

12 September 2017

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Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells

12 September 2017

1 reference

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Sigma receptors: potential medications development target for anti-cocaine agents

12 September 2017

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Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene

12 September 2017

1 reference

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High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase

12 September 2017

1 reference

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The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis

12 September 2017

1 reference

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Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)

12 September 2017

1 reference

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Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the sigma-1 receptor

12 September 2017

1 reference

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Mutational analysis of ABCG2: role of the GXXXG motif

14 September 2017

1 reference

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Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor

14 September 2017

1 reference

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Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors

25 September 2017

1 reference

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A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from that of guinea pig brain

15 June 2018

1 reference

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A 3D-pharmacophore model for sigma2 receptors based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives

15 June 2018

1 reference

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Synthesis, biological evaluation, and three-dimensional in silico pharmacophore model for sigma(1) receptor ligands based on a series of substituted benzo[d]oxazol-2(3H)-one derivatives

21 August 2018

1 reference

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Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening

21 August 2018

1 reference

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Successful virtual screening for a submicromolar antagonist of the neurokinin-1 receptor based on a ligand-supported homology model

21 August 2018

1 reference

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Ligand-supported Homology Modelling of Protein Binding-sites using Knowledge-based Potentials

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4017991

The sigma receptor as a ligand-regulated auxiliary potassium channel subunit

21 August 2018

1 reference

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Structural features important for sigma 1 receptor binding

21 August 2018

1 reference

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Ligand-supported homology modeling of g-protein-coupled receptor sites: models sufficient for successful virtual screening

21 August 2018

1 reference

12 December 2020

Structure-based drug discovery using GPCR homology modeling: successful virtual screening for antagonists of the alpha1A adrenergic receptor

1 reference

12 December 2020

A proposal for the classification of sigma binding sites

1 reference

12 December 2020

Identification of regions of the sigma-1 receptor ligand binding site using a novel photoprobe

1 reference

12 December 2020

Identifiers

DOI

10.1021/ML2001505

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20 March 2020

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24 November 2022

mapped directly with Wikidata item

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20 March 2020

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