A time-of-drug addition approach to target identification of antiviral compounds (Q39531429)

12 September 2017

A time-of-drug addition approach to target identification of antiviral compounds (English)

1 reference

12 September 2017

Dirk Daelemans

1

0 references

Christophe Pannecouque

object named as

Christophe Pannecouque

series ordinal

4

0 references

Erik De Clercq

object named as

Erik De Clercq

series ordinal

3

0 references

author name string

Rudi Pauwels

series ordinal

2

1 reference

12 September 2017

2 June 2011

1 reference

12 September 2017

1 reference

12 September 2017

6

1 reference

12 September 2017

925-933

1 reference

12 September 2017

6

1 reference

https://scigraph.springernature.com/pub.10.1038/nprot.2011.330

12 September 2017

0 references

cites work

Tetrazolium-based colorimetric assay for the detection of HIV replication inhibitors: revisited 20 years later

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Suramin: A potent inhibitor of the reverse transcriptase of RNA tumor viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

An intrabody based on a llama single-domain antibody targeting the N-terminal alpha-helical multimerization domain of HIV-1 rev prevents viral production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Suramin protection of T cells in vitro against infectivity and cytopathic effect of HTLV-III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Effects of suramin on HTLV-III/LAV infection presenting as Kaposi's sarcoma or AIDS-related complex: clinical pharmacology and suppression of virus replication in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Suramin in the treatment of AIDS: mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

L-chicoric acid, an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase, improves on the in vitro anti-HIV-1 effect of Zidovudine plus a protease inhibitor (AG1350).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Studies of anti-HIV transcription inhibitor quinolones: identification of potent N1-vinyl derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Inhibition of the CRM1-mediated nucleocytoplasmic transport by N-azolylacrylates: structure-activity relationship and mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

A novel and efficient approach to discriminate between pre- and post-transcription HIV inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

A quantitative GFP-based bioassay for the detection of HIV-1 Tat transactivation inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Complete inhibition of human immunodeficiency virus Gag myristoylation is necessary for inhibition of particle budding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

HIV-1: fifteen proteins and an RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Inhibition of HIV-1 replication by a bis-thiadiazolbenzene-1,2-diamine that chelates zinc ions from retroviral nucleocapsid zinc fingers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Inhibition of replication and cytopathic effect of human T cell lymphotropic virus type III/lymphadenopathy-associated virus by 3'-azido-3'-deoxythymidine in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Structure modifications of 6-aminoquinolones with potent anti-HIV activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2011.330

Assays for the evaluation of HIV-1 integrase inhibitors

21 January 2018

1 reference

12 December 2020

Continuous production of a cytopathic human T-lymphotropic virus in a permissive neoplastic T-cell line

1 reference

12 December 2020

Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters

1 reference

12 December 2020

A second target for the peptoid Tat/transactivation response element inhibitor CGP64222: inhibition of human immunodeficiency virus replication by blocking CXC-chemokine receptor 4-mediated virus entry

1 reference

12 December 2020

Inhibitors of retroviral DNA polymerase: their implication in the treatment of AIDS.

1 reference

12 December 2020

Polyanionic (i.e., polysulfonate) dendrimers can inhibit the replication of human immunodeficiency virus by interfering with both virus adsorption and later steps (reverse transcriptase/integrase) in the virus replicative cycle

1 reference

12 December 2020

Suramin inhibits binding of the V3 region of HIV-1 envelope glycoprotein gp120 to galactosylceramide, the receptor for HIV-1 gp120 on human colon epithelial cells.

1 reference

12 December 2020

Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

1 reference

12 December 2020

Identifiers

DOI

10.1038/NPROT.2011.330

1 reference

12 September 2017

1 reference

PubMed ID

21637207