Formaldehyde activation of mitoxantrone yields CpG and CpA specific DNA adducts (Q39542339)

12 September 2017

Formaldehyde activation of mitoxantrone yields CpG and CpA specific DNA adducts (English)

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12 September 2017

C Cullinane

3

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author name string

B S Parker

series ordinal

1

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12 September 2017

S M Cutts

series ordinal

2

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12 September 2017

D R Phillips

series ordinal

4

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12 September 2017

language of work or name

English

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publication date

1 February 2000

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12 September 2017

Nucleic Acids Research

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12 September 2017

28

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12 September 2017

4

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12 September 2017

982-990

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describes a project that uses

12 September 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC102576/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Characterization of covalent adriamycin-DNA adducts

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Production of formaldehyde from N5-methyltetrahydrofolate by normal and leukemic leukocytes

13 September 2017

1 reference

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Formation of DNA adducts by formaldehyde-activated mitoxantrone.

13 September 2017

1 reference

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Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA

14 September 2017

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Thermal stability of DNA adducts induced by cyanomorpholinoadriamycin in vitro.

14 September 2017

1 reference

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DNA sequence specificity of mitoxantrone

14 September 2017

1 reference

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Stability of adriamycin-induced DNA adducts and interstrand crosslinks

14 September 2017

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DNA adducts from chemotherapeutic agents

14 September 2017

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Quantitative confocal spectral imaging analysis of mitoxantrone within living K562 cells: intracellular accumulation and distribution of monomers, aggregates, naphtoquinoxaline metabolite, and drug-target complexes

25 September 2017

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Localization and molecular interactions of mitoxantrone within living K562 cells as probed by confocal spectral imaging analysis

15 June 2018

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DNA-protein cross-links produced by various chemicals in cultured human lymphoma cells.

15 June 2018

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Cytochrome P-450-induced cytotoxicity of mitoxantrone by formation of electrophilic intermediates

15 June 2018

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Mitoxantrone for the treatment of advanced breast cancer: single-agent therapy in previously untreated patients.

15 June 2018

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Formaldehyde mutagenesis and formation of DNA-protein crosslinks in human lymphoblasts in vitro

15 June 2018

1 reference

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Regulation of superoxide generation by myeloperoxidase during the respiratory burst of human neutrophils

15 June 2018

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Quantitative analysis by gas chromatography of volatile carbonyl compounds in expired air from mice and human

15 June 2018

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Intracellular pharmacokinetics of anthracyclines in human leukemia cells: correlation of DNA-binding with apoptotic cell death

21 August 2018

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12 December 2020

Isolation and identification of cross-links from formaldehyde-treated nucleic acids

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12 December 2020

Further studies on the generation of reactive oxygen species from activated anthracyclines and the relationship to cytotoxic action and cardiotoxic effects

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12 December 2020

Characteristics of the binding of the anticancer agents mitoxantrone and ametantrone and related structures to deoxyribonucleic acids

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12 December 2020

Induction of stable transcriptional blockage sites by Adriamycin: GpC specificity of apparent Adriamycin-DNA adducts and dependence on iron(III) ions

1 reference

12 December 2020

Cytosine methylation enhances mitomycin C cross-linking

1 reference

12 December 2020

Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin

1 reference

12 December 2020

Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin

1 reference

12 December 2020

Doxoform and Daunoform: anthracycline-formaldehyde conjugates toxic to resistant tumor cells

1 reference

12 December 2020

Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron

1 reference

12 December 2020

Synthesis, DNA binding, topoisomerase II inhibition and cytotoxicity of two guanidine-containing anthracene-9,10-diones

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12 December 2020

Clinical applications of anticancer drugs targeted to topoisomerase II

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/28.4.982

1 reference

12 September 2017

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12 September 2017

PubMed publication ID

10648792

1 reference