Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration (Q39556857)

13 September 2017

Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration (English)

1 reference

13 September 2017

5

Drew Weissman

1 reference

13 September 2017

Sundararajan Venkatesan

1

1 reference

13 September 2017

Ana Petrovic

2

1 reference

13 September 2017

Donald I Van Ryk

3

1 reference

13 September 2017

Massimo Locati

4

1 reference

13 September 2017

Philip M Murphy

6

1 reference

13 September 2017

language of work or name

English

0 references

publication date

16 October 2001

1 reference

Journal of Biological Chemistry

13 September 2017

1 reference

13 September 2017

277

1 reference

13 September 2017

3

1 reference

13 September 2017

2287-2301

1 reference

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

13 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

G protein-coupled receptors. I. Diversity of receptor-ligand interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Identification of a major co-receptor for primary isolates of HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Chemokines and chemokine receptors: biology and clinical relevance in inflammation and AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

A new classification for HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

HIV-1 infectability of CD4+ lymphocytes with relation to beta-chemokines and the CCR5 coreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

CXC Chemokines Bind to Unique Sets of Selectivity Determinants That Can Function Independently and Are Broadly Distributed on Multiple Domains of Human Interleukin-8 Receptor B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Determinants of HIV-1 coreceptor function on CC chemokine receptor 3. Importance of both extracellular and transmembrane/cytoplasmic regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Cloning and functional expression of a human eosinophil CC chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Heterodimerization is required for the formation of a functional GABA(B) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

G-protein-coupled receptor heterodimerization modulates receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

G protein coupled receptor dimerization: implications in modulating receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Identification and molecular characterization of m3 muscarinic receptor dimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

G-protein-coupled receptors function as oligomers in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

The chemokine SDF-1alpha triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Rhodopsin: structure, function, and genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

The molecular basis of nephrogenic diabetes insipidus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Truncated V2 vasopressin receptors as negative regulators of wild-type V2 receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Structural and functional aspects of G protein-coupled receptor oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Oligomerization of dopamine and serotonin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Functional significance of oligomerization of G-protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Oligomerization of G-protein-coupled transmitter receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Homo-oligomeric complexes of the yeast alpha-factor pheromone receptor are functional units of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Naturally occurring CCR5 extracellular and transmembrane domain variants affect HIV-1 Co-receptor and ligand binding function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of beta-chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

HIV blocked by chemokine antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108321200

21 January 2018

Identifiers

DOI

10.1074/JBC.M108321200

1 reference

13 September 2017

1 reference