MEK-ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes (Q39557396)

13 September 2017

MEK-ERK pathway regulates EZH2 overexpression in association with aggressive breast cancer subtypes (English)

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13 September 2017

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S Fujii

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K Tokita

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N Wada

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K Ito

4

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C Yamauchi

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Y Ito

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A Ochiai

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language of work or name

English

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publication date

18 April 2011

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39

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4118-4128

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https://scigraph.springernature.com/pub.10.1038/onc.2011.118

13 September 2017

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EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

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Triple-negative breast cancer: therapeutic options

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The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer

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Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.118

Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation

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https://api.crossref.org/works/10.1038%2FONC.2011.118

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

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BRCA1 mutations in primary breast and ovarian carcinomas.

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

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Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

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The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

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Quantitative association between HER-2/neu and steroid hormone receptors in hormone receptor-positive primary breast cancer

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Basal carcinoma of the breast revisited: an old entity with new interpretations.

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Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans.

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Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

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Molecular portraits of human breast tumours

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Role of histone H3 lysine 27 methylation in X inactivation

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BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.

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Coexpression of BMI-1 and EZH2 polycomb group genes in Reed-Sternberg cells of Hodgkin's disease

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Genome regulation by polycomb and trithorax proteins

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

21 January 2018

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.118

The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.118

p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.118

RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2011.118

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.118

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13 September 2017

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