BH3 mimetics activate multiple pro-autophagic pathways (Q39565305)

13 September 2017

BH3 mimetics activate multiple pro-autophagic pathways (English)

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13 September 2017

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G Kroemer

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Maria Chiara Maiuri

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object named as

M C Maiuri

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author name string

S A Malik

1

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13 September 2017

I Orhon

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E Morselli

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A Criollo

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S Shen

5

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G Mariño

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A BenYounes

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P Bénit

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P Rustin

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language of work or name

English

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publication date

4 April 2011

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13 September 2017

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30

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37

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3918-3929

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https://scigraph.springernature.com/pub.10.1038/onc.2011.104

13 September 2017

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The IKK complex contributes to the induction of autophagy

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

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To die or not to die: that is the autophagic question

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BH3-Only proteins-essential initiators of apoptotic cell death

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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1.

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A comprehensive glossary of autophagy-related molecules and processes

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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

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A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum

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Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

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Stimulation of autophagy by the p53 target gene Sestrin2.

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

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Programmed anuclear cell death delimits platelet life span.

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Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

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Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

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The autophagy effector Beclin 1: a novel BH3-only protein

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Regulation of autophagy by cytoplasmic p53

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p53 represses autophagy in a cell cycle-dependent fashion

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Mammalian autophagy: core molecular machinery and signaling regulation

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Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum.

21 January 2018

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Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy

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Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples

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BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L)

31 March 2020

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Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo

31 March 2020

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Biochemical and molecular investigations in respiratory chain deficiencies

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.104

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13 September 2017

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