DNA nuclear targeting sequences for non-viral gene delivery (Q39572746)

13 September 2017

DNA nuclear targeting sequences for non-viral gene delivery (English)

1 reference

13 September 2017

7

Wim E Hennink

1 reference

13 September 2017

6

Robbert Jan Kok

1 reference

13 September 2017

Ethlinn V B van Gaal

1

1 reference

13 September 2017

Ronald S Oosting

2

1 reference

13 September 2017

Roel van Eijk

3

1 reference

13 September 2017

Marta Bakowska

4

1 reference

13 September 2017

Dries Feyen

5

1 reference

13 September 2017

Daan J A Crommelin

8

1 reference

13 September 2017

Enrico Mastrobattista

9

1 reference

13 September 2017

18 March 2011

1 reference

13 September 2017

Pharmaceutical Research

1 reference

13 September 2017

28

1 reference

13 September 2017

7

1 reference

13 September 2017

1707-1722

1 reference

Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection

13 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Targeted delivery to the nucleus.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Intracellular trafficking of plasmids for gene therapy: mechanisms of cytoplasmic movement and nuclear import

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Nuclear entry of nonviral vectors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

NLS bioconjugates for targeting therapeutic genes to the nucleus.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

14 September 2017

The nuclear pore complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Size-dependent DNA mobility in cytoplasm and nucleus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Transport between the cell nucleus and the cytoplasm

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Sequence requirements for plasmid nuclear import

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area

14 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

14 September 2017

https://api.crossref.org/works/10.1007%2FS11095-011-0407-8

Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Synchronization of HeLa cell cultures by inhibition of DNA polymerase alpha with aphidicolin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Fluorescence in situ hybridization to monitor the intracellular location and accessibility of plasmid DNA delivered by cationic polymer-based gene carriers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Insertion of nuclear factor-kappaB binding sequence into plasmid DNA for increased transgene expression in colon carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Targeting of the glucocorticoid hormone receptor with plasmid DNA comprising glucocorticoid response elements improves nonviral gene transfer efficiency in the lungs of mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Cytoskeletal involvement in the cellular trafficking of plasmid/PEI derivative complexes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Nuclear localisation and pDNA condensation in non-viral gene delivery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Intracellular trafficking of plasmids during transfection is mediated by microtubules

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Cell-specific nuclear import of plasmid DNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Helper activity for gene expression, a novel function of the SV40 enhancer.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Nuclear-associated plasmid, but not cell-associated plasmid, is correlated with transgene expression in cultured mammalian cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Import of plasmid DNA into the nucleus is sequence specific

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

An assessment of relative transcriptional availability from nonviral vectors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

On the kinetics of polyplex endocytic trafficking: implications for gene delivery vector design.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin alpha.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

The efficiency of nuclear plasmid DNA delivery is a critical determinant of transgene expression at the single cell level

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Transgene expression of transfected supercoiled plasmid DNA concatemers in mammalian cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Intracellular DNA release and elimination correlate poorly with transgene expression after non-viral transfection

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

S4(13)-PV cell penetrating peptide and cationic liposomes act synergistically to mediate intracellular delivery of plasmid DNA.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Effect of peptides bearing nuclear localization signals on therapeutic ultrasound mediated gene delivery

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Smooth muscle-specific gene delivery in the vasculature based on restriction of DNA nuclear import

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

The role of actin and microtubule networks in plasmid DNA intracellular trafficking.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Transcription of plasmid DNA: influence of plasmid DNA/polyethylenimine complex formation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

The role of plasmid constructs containing the SV40 DNA nuclear-targeting sequence in cationic lipid-mediated DNA delivery

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Postmitotic nuclear retention of episomal plasmids is altered by DNA labeling and detection methods

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

An NLS peptide covalently linked to linear DNA does not enhance transfection efficiency of cationic polymer based gene delivery systems

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Factors influencing the ability of nuclear localization sequence peptides to enhance nonviral gene delivery

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Endosomal escape of polymeric gene delivery complexes is not always enhanced by polymers buffering at low pH.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

No Enhancement of Nuclear Entry by Direct Conjugation of a Nuclear Localization Signal Peptide to Linearized DNA

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

A regulated, NFkappaB-assisted import of plasmid DNA into mammalian cell nuclei

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Muscle-specific enhancement of gene expression by incorporation of SV40 enhancer in the expression plasmid

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Cationic lipid-mediated transfection of cells in culture requires mitotic activity

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109246

Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery

21 August 2018

1 reference

12 December 2020

Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes

1 reference

12 December 2020

Intracellular route and transcriptional competence of polyethylenimine-DNA complexes

1 reference

12 December 2020

Powerful and versatile enhancer-promoter unit for mammalian expression vectors

1 reference

12 December 2020

DNA vector chemistry: the covalent attachment of signal peptides to plasmid DNA

1 reference

12 December 2020

DNA injection into single cells of intact mice

1 reference

12 December 2020

A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA

1 reference

12 December 2020

Enhanced intracellular mobility and nuclear accumulation of DNA plasmids associated with a karyophilic protein

1 reference

12 December 2020

10.1007/S11095-011-0407-8

Identifiers

DOI

1 reference

release_ctfp7bqb65fdlby62hofnu5mpq

13 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ctfp7bqb65fdlby62hofnu5mpq

24 November 2022

mapped directly with Wikidata item

1 reference

13 September 2017

PubMed publication ID

21424159

1 reference