Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors. (Q39579208)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21386840%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors (English)

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24 January 2020

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3

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24 January 2020

Victor L Thijssen

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24 January 2020

author name string

I V Bijnsdorp

1

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24 January 2020

F Capriotti

2

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24 January 2020

N Losekoot

4

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24 January 2020

M Fukushima

5

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24 January 2020

A W Griffioen

6

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24 January 2020

G J Peters

8

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24 January 2020

language of work or name

English

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publication date

8 March 2011

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British Journal of Cancer

24 January 2020

published in

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24 January 2020

volume

104

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24 January 2020

issue

7

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24 January 2020

page(s)

1185-1192

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Increased migration by stimulation of thymidine phosphorylase in endothelial cells of different origin

24 January 2020

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1 reference

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2-Deoxy-D-ribose, a downstream mediator of thymidine phosphorylase, regulates tumor angiogenesis and progression

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14 September 2017

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14 September 2017

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Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors

14 September 2017

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14 September 2017

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Thymidine phosphorylase/platelet-derived endothelial cell growth factor is upregulated in advanced solid types of gastric cancer

14 September 2017

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Effects of platelet-derived endothelial cell growth factor/thymidine phosphorylase, substrate, and products in a three-dimensional model of angiogenesis

14 September 2017

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Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis

14 September 2017

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14 September 2017

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Angiogenic factor thymidine phosphorylase increases cancer cell invasion activity in patients with gastric adenocarcinoma.

14 September 2017

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14 September 2017

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2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9.

14 September 2017

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14 September 2017

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17 June 2018

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Identification of aspartic acid-203 in human thymidine phosphorylase as an important residue for both catalysis and non-competitive inhibition by the small molecule "crystallization chaperone" 5'-O-tritylinosine (KIN59).

21 August 2018

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21 August 2018

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21 August 2018

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Sulfasalazine down-regulates the expression of the angiogenic factors platelet-derived endothelial cell growth factor/thymidine phosphorylase and interleukin-8 in human monocytic-macrophage THP1 and U937 cells

21 August 2018

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21 August 2018

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21 August 2018

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21 August 2018

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Thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by specific activation of the integrins alpha 5 beta 1 and alpha V beta 3.

21 August 2018

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Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.

21 August 2018

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Angiogenic co-operation of VEGF and stromal cell TP in endometrial carcinomas

21 August 2018

1 reference

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Thymidine phosphorylase: its role in sensitivity and resistance to anticancer drugs.

21 August 2018

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Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2'-deoxyribonucleosides

21 August 2018

1 reference

12 December 2020

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in macrophages correlates with tumor angiogenesis and prognosis in invasive breast cancer

1 reference

12 December 2020

Thymidine phosphorylase expression is predominantly observed in stroma of well-differentiated adenocarcinoma of endometrium and correlates with a frequency of vascular involvement

1 reference

12 December 2020

Immunohistochemical localization of thymidine phosphorylase in gastric cancer: is there a role of the differential expression in tumor cells and associated stromal cells?

1 reference

12 December 2020

Expression of the angiogenic factor thymidine phosphorylase/platelet-derived endothelial cell growth factor in primary bladder cancers

1 reference

12 December 2020

Thymidine phosphorylase activity in human bladder cancer: difference between superficial and invasive cancer

1 reference

12 December 2020

Microtubule-targeting agents inhibit angiogenesis at subtoxic concentrations, a process associated with inhibition of Rac1 and Cdc42 activity and changes in the endothelial cytoskeleton

1 reference

12 December 2020

A sensitive non-radioactive assay for pyrimidine nucleoside phosphorylase using reversed-phase high performance liquid chromatography

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12 December 2020

Identifiers

DOI

10.1038/BJC.2011.74

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21386840%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21386840%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

21386840

1 reference