The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation (Q39580830)

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3 December 2019

title

The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation (English)

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3 December 2019

author name string

L E Hann

1

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3 December 2019

W J Cook

2

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3 December 2019

S L Uprichard

3

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3 December 2019

D M Knipe

4

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3 December 2019

D M Coen

5

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3 December 2019

language of work or name

English

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publication date

1 October 1998

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3 December 2019

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3 December 2019

volume

72

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3 December 2019

issue

10

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3 December 2019

page(s)

7709-7714

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ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif

3 December 2019

cites work

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Promoter-proximal poly(A) sites are processed efficiently, but the RNA products are unstable in the nucleus

14 September 2017

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The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

14 September 2017

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Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes

14 September 2017

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A herpes simplex virus type 1 immediate-early gene product, IE63, regulates small nuclear ribonucleoprotein distribution.

14 September 2017

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The acidic amino-terminal region of herpes simplex virus type 1 alpha protein ICP27 is required for an essential lytic function.

14 September 2017

1 reference

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Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport

14 September 2017

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Amino acid substitution mutations in the herpes simplex virus ICP27 protein define an essential gene regulation function.

14 September 2017

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The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection

14 September 2017

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Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect

14 September 2017

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The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location

14 September 2017

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The C-terminal repressor region of herpes simplex virus type 1 ICP27 is required for the redistribution of small nuclear ribonucleoprotein particles and splicing factor SC35; however, these alterations are not sufficient to inhibit host cell splicin

14 September 2017

1 reference

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Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4.

14 September 2017

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Arginine-rich regions succeeding the nuclear localization region of the herpes simplex virus type 1 regulatory protein ICP27 are required for efficient nuclear localization and late gene expression

14 September 2017

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14 September 2017

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Herpes simplex virus trans-regulatory protein ICP27 stabilizes and binds to 3' ends of labile mRNA.

14 September 2017

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Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1

14 September 2017

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Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1

14 September 2017

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In vitro transcription of the thymidine kinase gene of herpes simplex virus

14 September 2017

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Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site.

14 September 2017

1 reference

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Herpes simplex virus type 1 ICP27 is an essential regulatory protein.

14 September 2017

1 reference

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The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini

14 September 2017

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Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus

14 September 2017

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Gene-specific transactivation by herpes simplex virus type 1 alpha protein ICP27.

14 September 2017

1 reference

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The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.

14 September 2017

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Regulatory pathways governing HIV-1 replication

14 September 2017

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The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule

14 September 2017

1 reference

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Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities

14 September 2017

1 reference

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Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient

14 September 2017

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Patterns of polyadenylation site selection in gene constructs containing multiple polyadenylation signals

14 September 2017

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The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection

14 September 2017

1 reference

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Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.

14 September 2017

1 reference

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Molecular analyses of two poly(A) site-processing factors that determine the recognition and efficiency of cleavage of the pre-mRNA.

14 September 2017

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14 September 2017

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Translational regulation of herpes simplex virus DNA polymerase

14 September 2017

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Regulation of herpes simplex virus true late gene expression: sequences downstream from the US11 TATA box inhibit expression from an unreplicated template

14 September 2017

1 reference

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Herpes simplex virus infection selectively stimulates accumulation of beta interferon reporter gene mRNA by a posttranscriptional mechanism

14 September 2017

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Temperature-sensitive mutants of herpes simplex virus type 1 defective in lysis but not in transformation

14 September 2017

1 reference

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Shuttling of the herpes simplex virus type 1 regulatory protein ICP27 between the nucleus and cytoplasm mediates the expression of late proteins.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=110073

Identification of a competitive translation determinant in the 3' untranslated region of alfalfa mosaic virus coat protein mRNA.

14 September 2017

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Translational regulation of the human cytomegalovirus pp28 (UL99) late gene

14 September 2017

1 reference

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Herpes simplex virus type 1 protein IE63 affects the nuclear export of virus intron-containing transcripts

14 September 2017

1 reference

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Regulation of herpes simplex virus poly (A) site usage and the action of immediate-early protein IE63 in the early-late switch.

14 September 2017

1 reference

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GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases

14 September 2017

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Induction of transcription by a viral regulatory protein depends on the relative strengths of functional TATA boxes

14 September 2017

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mRNAs containing the unstructured 5' leader sequence of alfalfa mosaic virus RNA 4 translate inefficiently in lysates from poliovirus-infected HeLa cells

14 September 2017

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Regulation of poly(A) site selection in adenovirus.

14 September 2017

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A negative regulatory element in the human papillomavirus type 16 genome acts at the level of late mRNA stability

14 September 2017

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Herpes simplex virus IE63 acts at the posttranscriptional level to stimulate viral mRNA 3' processing

14 September 2017

1 reference

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The herpes simplex virus immediate-early protein ICP27 shuttles between nucleus and cytoplasm

14 September 2017

1 reference

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Poly(A) site efficiency reflects the stability of complex formation involving the downstream element

25 September 2017

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Preferential translation of reovirus mRNA by a sigma3-dependent mechanism

25 September 2017

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Herpes simplex virus type 1 immediate early protein IE63 shuttles between nuclear compartments and the cytoplasm

25 September 2017

1 reference

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Temporal regulation of herpes simplex virus type 1 UL24 mRNA expression via differential polyadenylation

17 June 2018

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In Vitro and in Vivo transcription initiation sites on the TK-encoding BamHI Q fragment of HSV-1 DNA

17 June 2018

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The products of herpes simplex virus type 1 (HSV-1) immediate early genes 1, 2 and 3 can activate HSV-1 gene expression in trans

17 June 2018

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Herpes simplex virus type 1 alpha gene containing plasmids can inhibit expression regulated from an alpha promoter in CV-1 but not HeLa cells

17 June 2018

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An ordered pathway of assembly of components required for polyadenylation site recognition and processing.

17 June 2018

1 reference

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Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation

17 June 2018

1 reference

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A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing

17 June 2018

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Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression

17 June 2018

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The association of herpes simplex virus with squamous carcinoma of the cervix, and studies of the virus thymidine kinase gene

17 June 2018

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Herpes simplex virus induces a processing factor that stimulates poly(A) site usage

21 August 2018

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Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing

21 August 2018

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12 December 2020

A genetic approach to promoter recognition during trans induction of viral gene expression

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12 December 2020

Definition of an efficient synthetic poly(A) site

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12 December 2020

A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs

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12 December 2020

Identifiers

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3 December 2019

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