GFAP promoter-driven RNA interference on TGF-β1 to treat liver fibrosis (Q39586742)

13 September 2017

GFAP promoter-driven RNA interference on TGF-β1 to treat liver fibrosis (English)

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13 September 2017

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Ningning Yang

1

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PubMed ID

21347569

13 September 2017

Ram I Mahato

series ordinal

2

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13 September 2017

23 February 2011

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13 September 2017

Pharmaceutical Research

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13 September 2017

28

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13 September 2017

4

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13 September 2017

752-761

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Mechanisms of hepatic fibrogenesis

13 September 2017

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

TGF-beta-induced fibrosis and SMAD signaling: oligo decoys as natural therapeutics for inhibition of tissue fibrosis and scarring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Liver fibrosis -- from bench to bedside

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

TGF-beta1 gene silencing for treating liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

RNA polymerase II mediated transcription from the polymerase III promoters in short hairpin RNA expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

The bone marrow functionally contributes to liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

GFAP promoter directs lacZ expression specifically in a rat hepatic stellate cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Therapeutic targeting of the PDGF and TGF-beta-signaling pathways in hepatic stellate cells by PTK787/ZK22258

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Bipartite vectors for co-expression of a growth factor cDNA and short hairpin RNA against an apoptotic gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Coexpression of vascular endothelial growth factor and interleukin-1 receptor antagonist for improved human islet survival and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Over-expressed microRNA-27a and 27b influence fat accumulation and cell proliferation during rat hepatic stellate cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Defining the optimal parameters for hairpin-based knockdown constructs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

MicroRNAs modulate hematopoietic lineage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

TGF-beta1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

Exploring hypotheses of the actions of TGF-beta1 in epidermal wound healing using a 3D computational multiscale model of the human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11095-011-0384-Y

The antifibrotic effect of TGF-beta1 siRNAs in murine model of liver cirrhosis

21 January 2018

1 reference

12 December 2020

Synthesis, formulation and in vitro evaluation of a novel microtubule destabilizer, SMART-100.

1 reference

12 December 2020

Prevention of CCl4-induced liver cirrhosis by ribbon antisense to transforming growth factor-beta1.

1 reference

12 December 2020

Loss of TGF-beta dependent growth control during HSC transdifferentiation

1 reference

12 December 2020

The bcl, NFkappaB and p53/p21WAF1 systems are involved in spontaneous apoptosis and in the anti-apoptotic effect of TGF-beta or TNF-alpha on activated hepatic stellate cells

1 reference

12 December 2020

10.1007/S11095-011-0384-Y

Identifiers

DOI

1 reference

13 September 2017

1 reference

PubMed ID

21347569