Focal cerebral ischemia: pathophysiologic mechanisms and rationale for future avenues of treatment (Q39592569)

13 September 2017

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title

Focal cerebral ischemia: pathophysiologic mechanisms and rationale for future avenues of treatment (English)

1 reference

13 September 2017

1 reference

1 reference

F B Meyer

1

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13 September 2017

T M Sundt

series ordinal

2

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13 September 2017

T Yanagihara

series ordinal

3

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13 September 2017

R E Anderson

series ordinal

4

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13 September 2017

language of work or name

English

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publication date

1 January 1987

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13 September 2017

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13 September 2017

volume

62

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13 September 2017

issue

1

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13 September 2017

page(s)

35-55

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Treatment of experimental cerebral ischemia

13 September 2017

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Mitochondrial metabolism following bilateral cerebral ischemia in the gerbil

7 January 2021

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Recovery of brain mitochondrial function in the rat after complete and incomplete cerebral ischemia

7 January 2021

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Effect of transient ischemia on free fatty acids and phospholipids in the gerbil brain. Lipid peroxidation as a possible cause of postischemic injury

7 January 2021

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Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Other Derivatives of Carbon-20 Unsaturated Fatty Acids

7 January 2021

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Excessive cellular acidosis: an important mechanism of neuronal damage in the brain?

7 January 2021

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Cerebral ischemia and reactive hyperemia. Studies of cortical blood flow and microcirculation before, during, and after temporary occlusion of middle cerebral artery of squirrel monkeys

7 January 2021

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Red Venous Blood: Occurrence and Significance in Ischemic and Nonischemic Cerebral Cortex

7 January 2021

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Reassessment of cerebral capillary changes in acute global ischemia and their relationship to the "no-reflow phenomenon"

7 January 2021

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Impaired microvascular filling after focal cerebral ischemia in monkeys

7 January 2021

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Neuronal alterations in developing cortical infarction. An experimental study in monkeys

7 January 2021

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Brain tissue pressure in focal cerebral ischemia

7 January 2021

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The blood-brain barrier to protein tracers in focal cerebral ischemia and infarction caused by occlusion of the middle cerebral artery

7 January 2021

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Immunohistochemical investigation of cerebral ischemia during recirculation

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Failure of prolonged hypocapnia, hypothermia, or hypertension to favorably alter acute stroke in primates

7 January 2021

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The effect of arterial hypertension of focal ischemic edema. An experimental study

7 January 2021

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7 January 2021

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Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat. I. Local cerebral blood flow and glucose utilization

7 January 2021

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Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat. II. Regional metabolite levels

7 January 2021

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7 January 2021

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7 January 2021

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Increased damage after ischemic stroke in patients with hyperglycemia with or without established diabetes mellitus

7 January 2021

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Experimental cerebral infarction: modification by treatment with hemodiluting, hemoconcentrating, and dehydrating agents

7 January 2021

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Hemodilution and anticoagulation. Effects on the microvasculature and microcirculation of the cerebral cortex after arterial occlusion

7 January 2021

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Failure of intravascular volume expansion without hemodilution to elevate cortical blood flow in region of experimental focal ischemia

7 January 2021

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Observations during hypervolemic hemodilution of patients with acute focal cerebral ischemia

7 January 2021

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A randomized controlled trial of hemodilution therapy in acute ischemic stroke

7 January 2021

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7 January 2021

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Hemorheology of the cerebral circulation in stroke

7 January 2021

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Pentoxifylline Does Not Protect Mice Against Hypoxia

7 January 2021

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Fibrinogen, blood viscosity, and cerebral ischemia

7 January 2021

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Controlled Trial of Ancrod in Ischemic Stroke

7 January 2021

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Modulation of the pathophysiology of primate focal cerebral ischaemia by indomethacin

7 January 2021

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LYSIS OF INTRACEREBRAL THROMBOEMBOLISM WITH FIBRINOLYSIN. REPORT OF A CASE

7 January 2021

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ANTICOAGULANTS PLUS STREPTOKINASE THERAPY IN PROGRESSIVE STROKE

7 January 2021

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A pilot study of urokinase therapy in cerebral infarction

7 January 2021

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Thrombolytic therapy for thromboembolism of vertebrobasilar artery

7 January 2021

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Tissue plasminogen activator reduces neurological damage after cerebral embolism.

7 January 2021

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Corticosteroids in ischemic stroke

7 January 2021

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The response of focal ischemic cerebral edema to dexamethasone

7 January 2021

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The Effect of Dexamethasone on the Edema of Focal Cerebral Ischemia

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Barbiturate protection in acute focal cerebral ischemia

7 January 2021

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Barbiturate attenuation of the clinical course and pathologic lesions in a primate stroke model

7 January 2021

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Delayed pentobarbital administration limits ischemic brain damage in gerbils

7 January 2021

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7 January 2021

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Barbiturate protection in focal cerebral ischemia

7 January 2021

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Barbiturate-induced coma therapy for focal cerebral ischemia. Effect after temporary and permanent MCA occlusion

7 January 2021

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Brain pH in focal cerebral ischemia and the protective effects of barbiturate anesthesia

7 January 2021

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Influence of anesthetics on metabolic, functional and pathological responses to regional cerebral ischemia

7 January 2021

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Inhibitory effects of different barbiturates on lipid peroxidation in brain tissue in vitro: comparison with the effects of promethazine and chlorpromazine.

7 January 2021

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Barbiturate Attenuation of Brain Free Fatty Acid Liberation During Global Ischemia

7 January 2021

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Barbiturate coma in focal cerebral ischemia. Relationship of protection to timing of therapy

7 January 2021

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Calcium Antagonists, Cerebral Ischemia and Vasospasm

7 January 2021

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Cerebral arterial spasm: part 9. In vitro effects of nifedipine on serotonin-, phenylephrine-, and potassium-induced contractions of canine basilar and femoral arteries

7 January 2021

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Effect of pretreatment with the calcium antagonist nimodipine on local cerebral blood flow and histopathology after middle cerebral artery occlusion

7 January 2021

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Nimodipine improves cerebral blood flow and neurologic recovery after complete cerebral ischemia in the dog

7 January 2021

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Cerebral blood flow and neurologic outcome when nimodipine is given after complete cerebral ischemia in the dog.

7 January 2021

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Effect of the Calcium Antagonist, Nimodipine, on Cerebral Blood Flow and Metabolism in the Primate

7 January 2021

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Effect of nimodipine on cerebral metabolism during ischemia and recirculation in the mongolian gerbil

7 January 2021

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The effects of a calcium antagonist, nimodipine, upon physiological responses of the cerebral vasculature and its possible influence upon focal cerebral ischaemia

7 January 2021

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Effects of verapamil and diltiazem on acute stroke in cats

7 January 2021

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Effect of the calcium antagonist nimodipine on the delayed hypoperfusion following incomplete ischemia in the rat

7 January 2021

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Effect of nimodipine on intracellular brain pH, cortical blood flow, and EEG in experimental focal cerebral ischemia

7 January 2021

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Effect of nimodipine (Bay e 9736) on postischaemic cerebrovascular reactivity, as revealed by measuring regional cerebral blood flow (rCBF).

7 January 2021

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Protective effect of Fluosol-DA in acute cerebral ischemia

7 January 2021

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The effect of Fluosol-DA on oxygen availability in focal cerebral ischemia

7 January 2021

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Fluorocarbon perfusion medium applied to the isolated rat brain

7 January 2021

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Modification of acute focal ischemia by treatment with mannitol

7 January 2021

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Treatment of acute focal ischemia with continuous CSF drainage and mannitol

7 January 2021

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Treatment of Acute Focal Cerebral Ischemia with Intermittent, Low Dose Mannitol

7 January 2021

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Experimental cerebral infarction. Part 3: Protective effect of mannitol in thalamic infarction in dogs

7 January 2021

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Impaired microvascular filling after focal cerebral ischemia in the monkey: Modification by treatment

7 January 2021

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NALOXONE REVERSAL OF ISCHAEMIC NEUROLOGICAL DEFICITS IN MAN

7 January 2021

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Reversal of Induced Ischemic Neurologic Deficit in Gerbils by the Opiate Antagonist Naloxone

7 January 2021

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Failure of naloxone to affect focal incomplete cerebral ischemia and collateral blood flow in cats

7 January 2021

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Naloxone therapy during focal cerebral ischemia evaluation in a primate model

7 January 2021

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A double blind trial of naloxone in the treatment of acute stroke

7 January 2021

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Naloxone or TRH fails to improve neurologic deficits in gerbil models of "stroke".

7 January 2021

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Failure of naloxone to reverse vascular neurologic deficits.

7 January 2021

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Naloxone administration to patients with acute stroke

7 January 2021

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Effects of naloxone on canine cerebral vascular smooth muscle

7 January 2021

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Time course of changes in catecholamines following right hemispheric cerebral infarction in the rat

7 January 2021

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Cathecholamine and 5-hydroxytryptamine levels in ischemic brain. Influence of p-chlorophenylalanine

7 January 2021

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Influence of endogenous norepinephrine on cerebral blood flow and metabolism

7 January 2021

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Treatment of acute focal cerebral ischemia with propranolol

7 January 2021

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Treatment of acute focal cerebral ischemia with propranolol

7 January 2021

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Improved neurological outcome in experimental focal cerebral ischemia treated with propranolol

7 January 2021

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Ethanol potentiation of central nervous system trauma

7 January 2021

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Lipid peroxidation in vivo induced by reversible global ischemia in rat brain

7 January 2021

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Free radicals in cerebral ischemia

7 January 2021

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Postischemic cerebral lipid peroxidation in vitro: modification by dietary vitamin E.

7 January 2021

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The protective effect of combined administration of anti-oxidants and perfluorochemicals on cerebral ischemia

7 January 2021

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No effect of prostacyclin on blood flow, regulation of blood flow and blood coagulation following global cerebral ischemia

7 January 2021

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Influence of prostacyclin on early morphological changes in the rabbit brain after complete 20-min ischemia

7 January 2021

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Treatment of acute focal cerebral ischemia with prostacyclin

7 January 2021

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Effect of intravenous eicosapentaenoic acid on cerebral blood flow, edema and brain prostaglandins in ischemic gerbils

7 January 2021

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Treatment of ischaemic stroke with prostacyclin.

7 January 2021

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Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain.

7 January 2021

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Calcium overload in selectively vulnerable neurons of the hippocampus during and after ischemia: an electron microscopy study in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Progress towards stroke prevention: Robert Wartenberg lecture

7 January 2021

1 reference

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Nature of occlusions of the middle cerebral artery

7 January 2021

1 reference

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LACUNES: SMALL, DEEP CEREBRAL INFARCTS.

7 January 2021

1 reference

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Arterial occlusions in the vertebro-basilar system. A study of 44 patients with post-mortem data

7 January 2021

1 reference

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Vertebrobasilar disease. Time for a new strategy

7 January 2021

1 reference

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The Harvard Cooperative Stroke Registry: A prospective registry

7 January 2021

1 reference

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Spontaneous resolution of occlusive lesions of the carotid artery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Indications for surgical intervention in middle cerebral artery obstruction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Sanguineous cerebrospinal fluid in recanalized cerebral infarction

7 January 2021

1 reference

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CEREBRAL EMBOLISM. ANGIOGRAPHIC OBSERVATIONS ON SPONTANEOUS CLOT LYSIS

7 January 2021

1 reference

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A RADIOLOGIC AND PATHOLOGIC STUDY OF EMBOLISM OF THE INTERNAL CAROTID-MIDDLE CEREBRAL ARTERIAL AXIS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Acute cerebral revascularization after regional cerebral ischemia in the dog. Part 2: Clinicopathological correlation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Effect of extracranial-intracranial bypass and pentobarbital on acute stroke in dogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Cerebral revascularization during barbiturate coma in primates and humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Emergency embolectomy for acute occlusion of the middle cerebral artery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Emergency carotid endarterectomy for patients with acute carotid occlusion and profound neurological deficits

7 January 2021

1 reference

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Temporal profile (clinical course) of acute carotid system cerebral infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Occlusion of the Carotid Artery: Prognosis (Natural History) and the Possibilities of Surgical Revascularization

7 January 2021

1 reference

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Predicting the outcome of stroke: acute stage after cerebral infarction

7 January 2021

1 reference

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Prognosis of cerebral embolism.

7 January 2021

1 reference

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Occlusion of the Middle Cerebral Artery: Serial Angiography as a Guide to Conservative Therapy

7 January 2021

1 reference

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Prognosis of patients with middle cerebral artery occlusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Thresholds of focal cerebral ischemia in awake monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Cerebral blood flow determined by hydrogen clearance during middle cerebral artery occlusion in unanesthetized monkeys

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Cerebral energy metabolism during transient ischemia and recovery in the gerbil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Cerebral ischemia in gerbils: polyribosomal function during progression and recovery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Nuclear binding sites for triiodothyronine in the gerbil brain following ischemia and recirculation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Transient cerebral ischemia and brain prostaglandins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Correlation of intracellular redox states and pH with blood flow in primary and secondary seizure foci.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Inhibition of electrically induced seizures by a dihydropyridine calcium channel blocker

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Cellular calcium metabolism, seizures, and ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Computed Tomography and EEG in Cerebrovascular Disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Repetitive involuntary movement associated with episodic cerebral ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Cerebral blood flow measurement in cerebrovascular occlusive diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Positron Imaging in Ischemic Stroke Disease Using Compounds Labeled With Oxygen 15

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Positron emission tomography and its application to the study of cerebrovascular disease in man.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Failure of extracranial-intracranial arterial bypass to reduce the risk of ischemic stroke. Results of an international randomized trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Results, complications, and follow-up of 415 bypass operations for occlusive disease of the carotid system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

Acute cerebral revascularization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

The concepts of thresholds of ischaemia in relation to brain structure and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

7 January 2021

Relationship between cerebral energy failure and free fatty acid accumulation following prolonged brain ischemia

1 reference

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7 January 2021

The Effects of Anesthesia and Hypothermia on Canine Cerebral ATP and Lactate during Anoxia Produced by Decapitation

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

7 January 2021

The Interdependency of Cerebral Functional and Metabolic Effects Following Massive Doses of Thiopental in the Dog

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

7 January 2021

Effects of beta-adrenergic blockade on cerebral autoregulation and chemical vasomotor control in patients with stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

7 January 2021

Cerebral metabolic changes during treatment of subacute cerebral infarction by alpha and beta adrenergic blockade with phenoxybenzamine and propranolol

1 reference

https://api.crossref.org/works/10.1016%2FS0025-6196%2812%2961523-7

7 January 2021

10.1016/S0025-6196(12)61523-7

Identifiers

DOI

1 reference

13 September 2017

1 reference