Regional difference in dynamical property of sinoatrial node pacemaking: role of na+ channel current (Q39594435)

13 September 2017

Regional difference in dynamical property of sinoatrial node pacemaking: role of na+ channel current (English)

1 reference

13 September 2017

Yasutaka Kurata

1

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13 September 2017

Hiroyuki Matsuda

series ordinal

2

1 reference

13 September 2017

Ichiro Hisatome

series ordinal

3

1 reference

13 September 2017

Toshishige Shibamoto

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4

1 reference

13 September 2017

language of work or name

English

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publication date

4 April 2008

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13 September 2017

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13 September 2017

95

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13 September 2017

2

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13 September 2017

951-977

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The integration of spontaneous intracellular Ca2+ cycling and surface membrane ion channel activation entrains normal automaticity in cells of the heart's pacemaker.

13 September 2017

1 reference

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The emergence of a general theory of the initiation and strength of the heartbeat

14 September 2017

1 reference

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Rhythmic Ca2+ oscillations drive sinoatrial nodal cell pacemaker function to make the heart tick.

14 September 2017

1 reference

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Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a

14 September 2017

1 reference

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A mathematical treatment of integrated Ca dynamics within the ventricular myocyte.

14 September 2017

1 reference

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A computational model of the human left-ventricular epicardial myocyte

14 September 2017

1 reference

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Diastolic calcium release controls the beating rate of rabbit sinoatrial node cells: numerical modeling of the coupling process.

14 September 2017

1 reference

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Biological pacemaker implanted in canine left bundle branch provides ventricular escape rhythms that have physiologically acceptable rates

14 September 2017

1 reference

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Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)

14 September 2017

1 reference

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Sophisticated architecture is required for the sinoatrial node to perform its normal pacemaker function

14 September 2017

1 reference

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Cyclic variation of intracellular calcium: a critical factor for cardiac pacemaker cell dominance

14 September 2017

1 reference

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An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release.

14 September 2017

1 reference

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Biological pacemaker created by gene transfer

14 September 2017

1 reference

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The sinoatrial node, a heterogeneous pacemaker structure

14 September 2017

1 reference

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Parasympathetic modulation of sinoatrial node pacemaker activity in rabbit heart: a unifying model

14 September 2017

1 reference

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Cardiac sodium channel Markov model with temperature dependence and recovery from inactivation

14 September 2017

1 reference

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Phase resetting and bifurcation in the ventricular myocardium

14 September 2017

1 reference

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Bursting, beating, and chaos by two functionally distinct inward current inactivations in excitable cells

14 September 2017

1 reference

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Three ways of abolishing automaticity in sinoatrial node: ionic modeling and nonlinear dynamics

14 September 2017

1 reference

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Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization

14 September 2017

1 reference

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Ion currents underlying sinoatrial node pacemaker activity: a new single cell mathematical model.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Ionic mechanisms of the cardiac pacemaker potential

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Dynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes: insights from bifurcation analyses of a mathematical model

25 September 2017

1 reference

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Role of individual ionic current systems in the SA node hypothesized by a model study.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Regional differences in the role of the Ca2+ and Na+ currents in pacemaker activity in the sinoatrial node.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Vagal control of sinoatrial rhythm: a mathematical model.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

A mathematical model of a rabbit sinoatrial node cell.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Mechanisms of sinoatrial pacemaker synchronization: a new hypothesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Bistabilities and annihilation phenomena in electrophysiological cardiac models

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

A model study of stability and oscillations in the myocardial cell membrane.

17 June 2018

1 reference

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Pacemaker activity of the rabbit sinoatrial node. A comparison of mathematical models

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Effects of pacemaker currents on creation and modulation of human ventricular pacemaker: theoretical study with application to biological pacemaker engineering.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families

21 August 2018

1 reference

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Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers

21 August 2018

1 reference

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Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes

21 August 2018

1 reference

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Rhythmic ryanodine receptor Ca2+ releases during diastolic depolarization of sinoatrial pacemaker cells do not require membrane depolarization

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

One-dimensional rabbit sinoatrial node models: benefits and limitations.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Intracellular Ca2+ and pacemaking within the rabbit sinoatrial node: heterogeneity of role and control

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Modeling beta-adrenergic control of cardiac myocyte contractility in silico

21 August 2018

1 reference

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Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking: insights from stability and bifurcation analyses of a mathematical model

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Expression and function of a biological pacemaker in canine heart

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Sarcoplasmic reticulum Ca2+ release is not a dominating factor in sinoatrial node pacemaker activity

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Analysis of the chronotropic effect of acetylcholine on sinoatrial node cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Heterogeneous expression of Ca(2+) handling proteins in rabbit sinoatrial node

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Role of I(K) and I(f) in the pacemaker mechanisms of sino-atrial node myocytes

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Mathematical models of action potentials in the periphery and center of the rabbit sinoatrial node.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Role of dual pacemaker mechanisms in sinoatrial node discharge.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Hopf bifurcations in multiple-parameter space of the Hodgkin-Huxley equations I. Global organization of bistable periodic solutions.

21 August 2018

1 reference

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Characterization of a TTX-sensitive Na+ current in pacemaker cells isolated from rabbit sinoatrial node.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Dynamics of abnormal pacemaking activity in cardiac Purkinje fibers.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Effects of simulated potassium blockade on the dynamics of triggered cardiac activity

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2440451

Relative densities of muscarinic cholinergic and beta-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity

21 August 2018

1 reference

12 December 2020

Somatic gene and cell therapy strategies for the treatment of cardiac arrhythmias

1 reference

12 December 2020

Electrophysiological study of the two main pacemaker mechanisms in the rabbit sinus node

1 reference

12 December 2020

Morphological study of the innervation pattern of the rabbit sinoatrial node

1 reference

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Modulation of pacemaker activity of sinoatrial node cells by electrical load imposed by an atrial cell model

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Ionic basis of ryanodine's negative chronotropic effect on pacemaker cells isolated from the sinoatrial node

1 reference

12 December 2020

Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

1 reference

12 December 2020

Computational evaluation of the roles of Na+ current, iNa, and cell death in cardiac pacemaking and driving

1 reference

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A spontaneously active focus drives a model atrial sheet more easily than a model ventricular sheet

1 reference

12 December 2020

Pacemaker shift in the rabbit sinoatrial node in response to vagal nerve stimulation

1 reference

12 December 2020

Atrio-sinus interaction demonstrated by blockade of the rapid delayed rectifier current

1 reference

12 December 2020

10.1529/BIOPHYSJ.107.112854

Identifiers

DOI

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release_3sfxfqidrzfzzpsrlm7tpdafs4

13 September 2017

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13 September 2017

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