SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors (Q39596870)

13 September 2017

title

SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors (English)

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13 September 2017

16

Daniel J Hicklin

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13 September 2017

Andrea D Basso

1

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13 September 2017

Ming Liu

2

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13 September 2017

Kimberly Gray

3

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13 September 2017

Seema Tevar

4

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13 September 2017

Suining Lee

5

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13 September 2017

Lianzhu Liang

6

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13 September 2017

Abdul Ponery

7

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13 September 2017

Elizabeth B Smith

8

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13 September 2017

Frederick J Monsma

9

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13 September 2017

Tao Yu

10

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13 September 2017

Yonglian Zhang

11

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13 September 2017

Angela D Kerekes

12

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13 September 2017

Sara Esposite

13

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13 September 2017

Yushi Xiao

14

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13 September 2017

Jayaram R Tagat

15

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13 September 2017

Paul Kirschmeier

17

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13 September 2017

publication date

5 February 2011

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Cancer Chemotherapy and Pharmacology

13 September 2017

published in

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13 September 2017

volume

68

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13 September 2017

issue

4

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13 September 2017

page(s)

923-933

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Aurora kinases as targets for cancer therapy

13 September 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Roles of Aurora kinases in mitosis and tumorigenesis.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora kinases: shining lights on the therapeutic horizon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora kinase inhibitors--rising stars in cancer therapeutics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

The suppression of aurora-A/STK15/BTAK expression enhances chemosensitivity to docetaxel in human esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Targeting aurora kinase with MK-0457 inhibits ovarian cancer growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

Chromatin-associated Protein Phosphatase 1 Regulates Aurora-B and Histone H3 Phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00280-011-1568-1

10.1007/S00280-011-1568-1

21 January 2018

Identifiers

DOI

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13 September 2017

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