Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells (Q39598785)

13 September 2017

Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells (English)

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13 September 2017

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Kathleen L O'Connor

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author name string

Min Chen

series ordinal

1

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PubMed ID

21289293

13 September 2017

Sarita K Sastry

series ordinal

2

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13 September 2017

2 February 2011

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American Journal of Physiology - Cell Physiology

13 September 2017

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13 September 2017

300

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13 September 2017

5

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13 September 2017

C1155-63

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Hyperosmolarity causes inflammation through the methylation of protein phosphatase 2A.

13 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Epithelial cyclooxygenase-2 expression: a model for pathogenesis of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Overexpression of S100A4 is closely related to the aggressiveness of gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

SRC family kinases in cell volume regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Increased cancer risk of augmentation cystoplasty: possible role for hyperosmolal microenvironment on DNA damage recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Activity of the TonEBP/OREBP transactivation domain varies directly with extracellular NaCl concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Metastasis-inducing S100A4 protein: implication in non-malignant human pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

The metastasis associated protein S100A4: role in tumour progression and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Patterns of duodenal osmolality in young pigs fed solid food

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Phospholipase C-gamma1 is involved in signaling the activation by high NaCl of the osmoprotective transcription factor TonEBP/OREBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Src kinases as therapeutic targets for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Fyn and p38 signaling are both required for maximal hypertonic activation of the osmotic response element-binding protein/tonicity-responsive enhancer-binding protein (OREBP/TonEBP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Discovery of osmosensitive transcriptional regulation of human cytochrome P450 3As by the tonicity-responsive enhancer binding protein (nuclear factor of activated T cells 5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

What sets the TonE during osmotic stress?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Post-prandial changes of osmolality and electrolyte concentration in the upper jejunum of normal man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Evidence for nucleosome depletion at active regulatory regions genome-wide

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Osmosignaling and volume regulation in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

S100A4 expression is associated with lymph node metastasis in papillary microcarcinoma of the thyroid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Analysis of gene expression in cancer cell lines identifies candidate markers for pancreatic tumorigenesis and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Hyperosmotic stress induces nuclear factor-kappaB activation and interleukin-8 production in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Expression of the calcium-binding protein S100A4 is markedly up-regulated by osmotic stress and is involved in the renal osmoadaptive response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Hyperosmotic stress contributes to mouse colonic inflammation through the methylation of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Is inflammation a consequence of extracellular hyperosmolarity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

Hypomethylation-induced expression of S100A4 in endometrial carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

MAPK mediation of hypertonicity-stimulated cyclooxygenase-2 expression in renal medullary collecting duct cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00407.2010

10.1152/AJPCELL.00407.2010

21 January 2018

Identifiers

DOI

1 reference

13 September 2017

1 reference

PubMed ID

21289293