Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma (Q39604051)

13 September 2017

Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma (English)

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13 September 2017

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A Caignard

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Mathilde Allard

object named as

M Allard

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Nadine Gervois

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N Gervois

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author name string

A Perier

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13 September 2017

G Fregni

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13 September 2017

S Wittnebel

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13 September 2017

S Gad

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13 September 2017

B Escudier

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13 September 2017

B Azzarone

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13 September 2017

language of work or name

English

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publication date

24 January 2011

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13 September 2017

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13 September 2017

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23

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13 September 2017

2622-2632

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describes a project that uses

13 September 2017

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https://scigraph.springernature.com/pub.10.1038/onc.2010.638

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cites work

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IL-6 as an intracrine growth factor for renal carcinoma cell lines

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Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma?

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Treatment selection for patients with metastatic renal cell carcinoma

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Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer.

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HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

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How Stat1 mediates constitutive gene expression: a complex of unphosphorylated Stat1 and IRF1 supports transcription of the LMP2 gene

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2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways

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Analysis of NK cells and chemokine receptors in tumor infiltrating CD4 T lymphocytes in human renal carcinomas.

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Intratumoural and peripheral blood lymphocyte subsets in patients with metastatic renal cell carcinoma undergoing interleukin-2 based immunotherapy: association to objective response and survival

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Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

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Mutations in BHD and TP53 genes, but not in HNF1beta gene, in a large series of sporadic chromophobe renal cell carcinoma

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DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors

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Mutations of the VHL tumour suppressor gene in renal carcinoma

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Transcriptional regulation of the MHC class Ib genes HLA-E, HLA-F, and HLA-G.

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Strict regulation of CAIX(G250/MN) by HIF-1alpha in clear cell renal cell carcinoma

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Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13.

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Regulation of STRA13 by the von Hippel-Lindau tumor suppressor protein, hypoxia, and the UBC9/ubiquitin proteasome degradation pathway

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Extracellular matrix composition and hypoxia regulate the expression of HLA-G and integrins in a human trophoblast cell line.

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Pro-inflammatory and T cell inhibitory cytokines are secreted at high levels in tumor cell cultures of human renal cell carcinoma

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Hereditary kidney cancer: unique opportunity for disease-based therapy.

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling

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Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

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Unravelling natural killer cell function: triggering and inhibitory human NK receptors

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Hypoxia modulates HLA-G gene expression in tumor cells.

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Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma

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Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma

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Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma

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Antigen-processing machinery breakdown and tumor growth

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Genetic and epigenetic alterations in the von hippel-lindau gene: the influence on renal cancer prognosis.

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Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts

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Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. Groupe Français d'Immunothérapie

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Renal cell carcinoma-infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes

31 March 2020

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Expression of the chemokine receptor CXCR1 in human glomerular diseases

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VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.638

1 reference

13 September 2017

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