Progress and prospects for optimum antiarrhythmic drug design (Q39612707)

13 September 2017

1 reference

title

Progress and prospects for optimum antiarrhythmic drug design (English)

1 reference

13 September 2017

K R Courtney

1

1 reference

13 September 2017

1 August 1987

1 reference

Cardiovascular Drugs and Therapy

13 September 2017

1 reference

13 September 2017

1

1 reference

13 September 2017

2

1 reference

13 September 2017

117-123

1 reference

Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

13 September 2017

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Re-entrant ventricular arrhythmias in the late myocardial infarction period. 2. Patterns of initiation and termination of re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Cellular mechanisms for cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Antiarrhythmic drug action. Blockade of the inward sodium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Pharmacologic conversion and suppression of experimental canine atrial flutter: differing effects of d-sotalol, quinidine, and lidocaine and significance of changes in refractoriness and conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Reconstruction of the action potential of ventricular myocardial fibres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Ionic basis of the different action potential configurations of single guinea-pig atrial and ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Test of a model of antiarrhythmic drug action. Effects of quinidine and lidocaine on myocardial conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Importance of physico-chemical properties in determining the kinetics of the effects of Class I antiarrhythmic drugs on maximum rate of depolarization in guinea-pig ventricle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02125464

Role of electrophysiologic studies in identifying arrhythmogenic properties of antiarrhythmic drugs

21 January 2018

1 reference

12 December 2020

Effects of tocainide and lidocaine on the transmembrane action potentials as related to external potassium and calcium concentrations in guinea-pig papillary muscles

1 reference

12 December 2020

Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics

1 reference

12 December 2020

Rate, rhythm and voltage dependent effects of phenytoin: a test of a model of the mechanisms of action of antiarrhythmic drugs

1 reference

12 December 2020

Mechanism for bupivacaine depression of cardiac conduction: fast block of sodium channels during the action potential with slow recovery from block during diastole.

1 reference

12 December 2020

Effect of lidocaine and quinidine on steady-state characteristics and recovery kinetics of (dV/dt)max in guinea pig ventricular myocardium

1 reference

12 December 2020

Fundamental properties of local anesthetics. I. The dependence of lidocaine's ionization and octanol:buffer partitioning on solvent and temperature.

1 reference

12 December 2020

Implications from electrophysiological differences resulting from small structural changes in antiarrhythmic drugs

1 reference

12 December 2020

Effects of pharmacologic agents on induced atrial flutter in dogs with right atrial enlargement

1 reference

12 December 2020

Effects of acebutolol and other structurally related beta adrenergic blockers on transmembrane action potential in guinea-pig papillary muscles

1 reference

12 December 2020

Aggravation of ventricular arrhythmia. A drug-induced complication

1 reference

12 December 2020

Cardiac Arrest Following Regional Anesthesia with Etidocaine or Bupivacaine

1 reference

12 December 2020

Lidocaine block of cardiac sodium channels

1 reference

12 December 2020

Inhibiton of $$\dot V_{\max } $$ of the action potential by propafenone and its voltage-, time- and pH-dependence in mammalian ventricular myocardium

1 reference

12 December 2020

Quantitative structure/activity relations based on use-dependent block and repriming kinetics in myocardium

1 reference

12 December 2020

Antiarrhythmic drug therapy: new drugs and changing concepts

1 reference

12 December 2020

PH-Dependent effects of quinidine on the kinetics of dV/dtmax in guinea pig ventricular myocardium

1 reference

12 December 2020

Local anesthetics: hydrophilic and hydrophobic pathways for the drug-receptor reaction

1 reference

12 December 2020

Effects of various structurally related beta-adrenoceptor blocking agents on maximum upstroke velocity of action potential in guinea-pig papillary muscles

1 reference

12 December 2020

Quantifying antiarrhythmic drug blocking during action potentials in guinea-pig papillary muscle

1 reference

12 December 2020

Interval-dependent effects of small antiarrhythmic drugs on excitability of guinea-pig myocardium

1 reference

12 December 2020

Kinetics of onset of rate-dependent effects of Class I antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification

1 reference

12 December 2020

pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium

1 reference

12 December 2020

Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02125464

1 reference

13 September 2017

1 reference

PubMed ID

3154314