Mutational Analysis of the PTEN Gene and Its Effects in Esophageal Squamous Cell Carcinoma (Q39626053)

13 September 2017

title

Mutational analysis of the PTEN gene and its effects in esophageal squamous cell carcinoma (English)

1 reference

13 September 2017

Mutational Analysis of the PTEN Gene and Its Effects in Esophageal Squamous Cell Carcinoma (English)

1 reference

https://api.crossref.org/works/10.1007/S10620-010-1474-0

esophageal squamous cell carcinoma

4 September 2024

main subject

1 reference

1 reference

Guiqin Hou

1

1 reference

13 September 2017

Zhaoming Lu

2

1 reference

13 September 2017

Mingyue Liu

3

1 reference

13 September 2017

Hongmin Liu

4

1 reference

13 September 2017

Lexun Xue

5

1 reference

13 September 2017

language of work or name

1 reference

30 November 2010

1 reference

full work available at URL

13 September 2017

http://link.springer.com/content/pdf/10.1007/s10620-010-1474-0.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/S10620-010-1474-0

http://link.springer.com/article/10.1007/s10620-010-1474-0/fulltext.html

4 September 2024

1 reference

https://api.crossref.org/works/10.1007/S10620-010-1474-0

http://link.springer.com/content/pdf/10.1007/s10620-010-1474-0

4 September 2024

1 reference

https://api.crossref.org/works/10.1007/S10620-010-1474-0

Digestive Diseases and Sciences

4 September 2024

published in

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13 September 2017

volume

56

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13 September 2017

issue

5

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13 September 2017

page(s)

1315-1322

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Estimates of the worldwide incidence of 25 major cancers in 1990.

13 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review

21 January 2018

1 reference

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Will the real Cowden syndrome please stand up (again)? Expanding mutational and clinical spectra of the PTEN hamartoma tumour syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Prognostic significance of PTEN expression in esophageal squamous cell carcinoma from Linzhou City, a high incidence area of northern China

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Nuclear factor-kB signaling pathway constitutively activated in esophageal squamous cell carcinoma cell lines and inhibition of growth of cells by small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies

21 January 2018

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Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

mTOR inhibitor rapamycin alone or combined with cisplatin inhibits growth of esophageal squamous cell carcinoma in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

21 January 2018

1 reference

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Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

21 January 2018

1 reference

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Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

Mutational analysis of the PTEN/MMAC1 gene in primary oesophageal squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10620-010-1474-0

MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines

21 January 2018

1 reference

12 December 2020

In vitro and in vivo evaluation of US-NCI compounds in human tumor xenografts

1 reference

12 December 2020

Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis

1 reference

12 December 2020

PTEN polymorphisms and the risk of esophageal carcinoma and gastric cardiac carcinoma in a high incidence region of China

1 reference

12 December 2020

Chromosome 10 alterations in prostate adenocarcinoma (review)

1 reference

12 December 2020

Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage.

1 reference

12 December 2020

PTEN/MMAC1 expression in esophageal squamous cell carcinomas.

1 reference

12 December 2020

PTEN regulatory functions in tumor suppression and cell biology

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12 December 2020

Medical Science Monitor

23

10

RA235

EC Chu

2004

1 reference

https://api.crossref.org/works/10.1007/S10620-010-1474-0

4 September 2024

Identifiers

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13 September 2017

1 reference