Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells (Q39641608)

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scientific article published on 21 October 2010

Language	Label	Description	Also known as
English	Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells	scientific article published on 21 October 2010

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Nobiletin, a citrus flavonoid, suppresses invasion and migration involving FAK/PI3K/Akt and small GTPase signals in human gastric adenocarcinoma AGS cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

1 reference

based on heuristic

inferred from title

0 references

gastric adenocarcinoma

1 reference

based on heuristic

inferred from title

author name string

Yi-Chieh Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Tsan-Hwang Cheng

2

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Europe PubMed Central

PubMed publication ID

13 September 2017

Jung-Shin Lee

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Jiun-Hwan Chen

4

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Europe PubMed Central

PubMed publication ID

13 September 2017

Yi-Chen Liao

5

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Europe PubMed Central

PubMed publication ID

13 September 2017

Yao Fong

6

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Europe PubMed Central

PubMed publication ID

13 September 2017

Cheng-Hsun Wu

7

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Europe PubMed Central

PubMed publication ID

13 September 2017

Yuan-Wei Shih

8

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Europe PubMed Central

PubMed publication ID

13 September 2017

publication date

21 October 2010

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Europe PubMed Central

PubMed publication ID

13 September 2017

Molecular and Cellular Biochemistry

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Europe PubMed Central

PubMed publication ID

13 September 2017

347

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13 September 2017

1-2

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Europe PubMed Central

PubMed publication ID

13 September 2017

103-115

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Europe PubMed Central

PubMed publication ID

13 September 2017

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrin-regulated FAK-Src signaling in normal and cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor cell invasion in the Boyden chamber assay by a mannosidase inhibitor, mannostatin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both focal adhesion kinase and c-Ras are required for the enhanced matrix metalloproteinase 9 secretion by fibronectin in ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase: a potential target in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group IB secretory phospholipase A2 promotes matrix metalloproteinase-2-mediated cell migration via the phosphatidylinositol 3-kinase and Akt pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of naturally occurring polymethyoxyflavonoids on cell growth, p-glycoprotein function, cell cycle, and apoptosis of daunorubicin-resistant T lymphoblastoid leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FAK signaling in neoplastic disorders: a linkage between inflammation and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of focal adhesion kinase in cellular invasion of head and neck squamous cell carcinomas via regulation of MMP-2 expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordination of cell signaling, chromatin remodeling, histone modifications, and regulator recruitment in human matrix metalloproteinase 9 gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid microscale procedure for the simultaneous preparation of cytoplasmic RNA, nuclear DNA binding proteins and enzymatically active luciferase extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Inhibition effect and its mechanism of nobiletin on proliferation of lung cancer cells].

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCL5 increases lung cancer migration via PI3K, Akt and NF-kappaB pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3',4'-didemethylnobiletin, derived from nobiletin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of focal adhesion kinase and phosphatidylinositol 3'-kinase in integrin fibronectin receptor-mediated, matrix metalloproteinase-1-dependent invasion by metastatic prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase: the first ten years

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR, ErbB2 and Ras but not Src suppress RhoB expression while ectopic expression of RhoB antagonizes oncogene-mediated transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nobiletin, a citrus flavonoid, down-regulates matrix metalloproteinase-7 (matrilysin) expression in HT-29 human colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2 -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho-family GTPases: it's not only Rac and Rho (and I like it).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric cancer epidemiology and risk factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoid composition of fruit tissues of citrus species

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agents targeting ras signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biology of integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A citrus polymethoxyflavonoid, nobiletin, is a novel MEK inhibitor that exhibits antitumor metastasis in human fibrosarcoma HT-1080 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total antioxidant potential of fruit and vegetables and risk of gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic effect of citrus fruit extract nobiletin on lung cancer cell line A549 in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for FAK in the Concanavalin A-dependent secretion of matrix metalloproteinase-2 and -9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nobiletin, a citrus flavonoid that improves memory impairment, rescues bulbectomy-induced cholinergic neurodegeneration in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mulberry leaf extract inhibits vascular smooth muscle cell migration involving a block of small GTPase and Akt/NF-kappaB signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rac1 promotes TGF-beta-stimulated mesangial cell type I collagen expression through a PI3K/Akt-dependent mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20963626

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11010-010-0618-Z

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

0 references

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