Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells (Q39645396)

13 September 2017

Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells (English)

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13 September 2017

Yoshiaki Kariya

1

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13 September 2017

Masashi Honma

2

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13 September 2017

Akiko Hanamura

3

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13 September 2017

Shigeki Aoki

4

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13 September 2017

Tadashi Ninomiya

5

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13 September 2017

Yuko Nakamichi

6

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13 September 2017

Nobuyuki Udagawa

7

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13 September 2017

Hiroshi Suzuki

8

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13 September 2017

1 April 2011

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Journal of Bone and Mineral Research

13 September 2017

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13 September 2017

26

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13 September 2017

4

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13 September 2017

689-703

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13 September 2017

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What is the true nature of the osteoblastic hematopoietic stem cell niche?

21 January 2018

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gp130 Cytokine family and bone cells

21 January 2018

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Regulatory mechanisms of osteoblast and osteoclast differentiation

21 January 2018

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RANK is essential for osteoclast and lymph node development

21 January 2018

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

21 January 2018

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Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

21 January 2018

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TNF receptor type 1 regulates RANK ligand expression by stromal cells and modulates osteoclastogenesis

21 January 2018

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Prostaglandin E2 induces expression of receptor activator of nuclear factor-kappa B ligand/osteoprotegrin ligand on pre-B cells: implications for accelerated osteoclastogenesis in estrogen deficiency

21 January 2018

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TNFalpha and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics

21 January 2018

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Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast cell lineage and stromal cells in a murine model of osteoclast differentiation

21 January 2018

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Vps33a mediates RANKL storage in secretory lysosomes in osteoblastic cells.

21 January 2018

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Rab proteins as membrane organizers

21 January 2018

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Slp4-a/granuphilin-a interacts with syntaxin-2/3 in a Munc18-2-dependent manner.

21 January 2018

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Involvement of the Rab27 binding protein Slac2c/MyRIP in insulin exocytosis

21 January 2018

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Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

21 January 2018

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Rab27a is required for regulated secretion in cytotoxic T lymphocytes

21 January 2018

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Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport

21 January 2018

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Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.

21 January 2018

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Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

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Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse

21 January 2018

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CTL secretory lysosomes: biogenesis and secretion of a harmful organelle

21 January 2018

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Identification of novel MUNC13-4 mutations in familial haemophagocytic lymphohistiocytosis and functional analysis of MUNC13-4-deficient cytotoxic T lymphocytes

21 January 2018

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The roles of Rab27 and its effectors in the regulated secretory pathways

21 January 2018

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Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms

21 January 2018

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MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1alpha

21 January 2018

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Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover

21 January 2018

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Regulation of secretory vesicle traffic by Rab small GTPases

21 January 2018

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Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis

21 January 2018

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Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system.

21 January 2018

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Rab27 and its effectors in secretory granule exocytosis: a novel docking machinery composed of a Rab27.effector complex

21 January 2018

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21 January 2018

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Constitutive GDP/GTP exchange and secretion-dependent GTP hydrolysis activity for Rab27 in platelets

21 January 2018

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Upregulation of FasL by LPA on ovarian cancer cell surface leads to apoptosis of activated lymphocytes

21 January 2018

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The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse

21 January 2018

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Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells

21 January 2018

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Delivering the kiss of death

21 January 2018

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Molecular cloning and characterization of rab27a and rab27b, novel human rab proteins shared by melanocytes and platelets

21 January 2018

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Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

21 January 2018

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Rab27b regulates number and secretion of platelet dense granules

21 January 2018

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The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.

21 January 2018

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Rab27 effector granuphilin promotes the plasma membrane targeting of insulin granules via interaction with syntaxin 1a.

21 January 2018

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Promoter structure of mouse RANKL/TRANCE/OPGL/ODF gene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBMR.268

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13 September 2017

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